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Foxn1tm2Nrm
Targeted Allele Detail
Summary
Symbol: Foxn1tm2Nrm
Name: forkhead box N1; targeted mutation 2, Nancy R Manley
MGI ID: MGI:3760773
Synonyms: Foxn1ex9lacZ, Foxn1-IRES-LacZ
Gene: Foxn1  Location: Chr11:78248403-78277384 bp, - strand  Genetic Position: Chr11, 46.74 cM
Alliance: Foxn1tm2Nrm page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:125817
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Reporter)
Mutation:    Insertion
 
Mutation detailsAn IRES-lacZ and floxed or frt neo cassette were inserted into the 3' end of exon 9. Insertion was confirmed by PCR of genomic DNA. A beta-galactosidase assay was used to confirm expression from the lacZ gene. RT-PCR was used to confirm that endogenous gene expression was unaffected. (J:125817)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Foxn1 Mutation:  106 strains or lines available
Notes
ES cell line strain = 129/Sv or C57BL/6
References
Original:  J:125817 Gordon J, et al., Specific expression of lacZ and cre recombinase in fetal thymic epithelial cells by multiplex gene targeting at the Foxn1 locus. BMC Dev Biol. 2007;7:69
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory