Mtrr In situ reporter (knock in) Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:121477 Elmore CL, et al., Metabolic derangement of methionine and folate metabolism in mice deficient in methionine synthase reductase. Mol Genet Metab. 2007 May;91(1):85-97
Assay type:	In situ reporter (knock in)
MGI Accession ID:	MGI:3711060
Gene symbol:	Mtrr
Gene name:	5-methyltetrahydrofolate-homocysteine methyltransferase reductase

Reporter:	lacZ
	Direct Detection
Assay notes:	The tissue was fixed in 0.2% glutaraldehyde.

Results

Specimen 5a side view (left): embryonic day 9.5; Mtrr^Gt(XG334)Byg/Mtrr⁺ (more

)

Structure	Level	Pattern	Image	Note
TS15: embryo	Present	Ubiquitous	5A left-side view	Expression is ubiquitous throughout the entire embryo.
TS15: optic vesicle	Strong		5A left-side view , 5A higher mag side view	There is strong expression in the optic eminence.
TS15: diencephalon	Strong		5A higher mag side view , 5A left-side view
TS15: telencephalon	Strong		5A left-side view , 5A higher mag side view
TS15: future midbrain	Strong		5A higher mag side view , 5A left-side view
TS15: rhombomere 2	Strong		5A left-side view , 5A higher mag side view
TS15: rhombomere 4	Strong		5A higher mag side view , 5A left-side view
TS15: 1st branchial arch	Strong		5A left-side view , 5A higher mag side view
TS15: foregut	Strong		5A left-side view
TS15: hindgut	Strong		5A left-side view

Specimen 5a dorsal view: embryonic day 9.5; Mtrr^Gt(XG334)Byg/Mtrr⁺ (more

)

Structure	Level	Pattern	Image	Note
TS15: embryo	Present	Ubiquitous	5A dorsal view	Expression is ubiquitous throughout the entire embryo.
TS15: 1st branchial arch	Strong		5A dorsal view
TS15: neural tube	Strong		5A dorsal view

Specimen 5a (right): embryonic day 9.5; Mtrr^Gt(XG334)Byg/Mtrr⁺ (more

)

Structure	Level	Pattern	Image	Note
TS15: embryo mesenchyme	Strong	Regionally restricted	5A right	There is strong expression in the splanchnic mesoderm.

Specimen 5c: embryonic day 9.5; Mtrr^Gt(XG334)Byg/Mtrr⁺ (more

)

Structure	Level	Pattern	Image	Note
TS28: placenta	Present	Regionally restricted	5C left , 5C right	Expression is present in the labyrinth layer.

Specimen Not shown: embryonic day 9.5; Mtrr^Gt(XG334)Byg/Mtrr⁺ (more

)

Structure	Level	Pattern	Image	Note
TS15: notochord	Present

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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