Arvcftm1Ais
Targeted Allele Detail
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Symbol: |
Arvcftm1Ais |
Name: |
armadillo repeat gene deleted in velocardiofacial syndrome; targeted mutation 1, Arthur I Skoultchi |
MGI ID: |
MGI:3702625 |
Gene: |
Arvcf Location: Chr16:18166046-18225826 bp, + strand Genetic Position: Chr16, 11.37 cM
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Alliance: |
Arvcftm1Ais page
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Germline Transmission: |
Earliest citation of germline transmission:
J:64380
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Parent Cell Line: |
WW6 (ES Cell)
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Strain of Origin: |
STOCK 129/Sv and C57BL/6J and SJL
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A targeting vector containing two regions of the armadillo repeat gene deleted in velo-cardio-facial syndrome flanking a hygromycin resistance gene, a loxP site and a promoterless puromycin resistance gene was inserted into the locus. The insertion of this vector resulted in the loss of amino acids 83-276.
(J:64380)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Arvcf Mutation: |
85 strains or lines available
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Original: |
J:64380 Puech A, et al., Normal cardiovascular development in mice deficient for 16 genes in 550 kb of the velocardiofacial/DiGeorge syndrome region. Proc Natl Acad Sci U S A. 2000 Aug 29;97(18):10090-5 |
All: |
1 reference(s) |
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