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Gene Expression Data
Assay Details
Assay
Reference: J:116140 Nam JS, et al., Dynamic expression of R-spondin family genes in mouse development. Gene Expr Patterns. 2007 Jan;7(3):306-12
Assay type: RNA in situ
MGI Accession ID: MGI:3698277
Gene symbol: Rspo2
Gene name: R-spondin 2
Probe: Rspo2 cDNA1
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen Not shown: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: embryo Absent

Specimen 1C: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: 1st branchial pouch Weak 1C
TS13: future midbrain Weak Regionally restricted 1C Expression is in the anterior midbrain.

Specimen 1G: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future forebrain Present Regionally restricted 1G Expression is dorsal.
TS15: future hindbrain Present Regionally restricted 1G Expression is at the midbrain/hindbrain junction and in the rostral hindbrain.
TS15: future midbrain Present Regionally restricted 1G Expression is at the midbrain/hindbrain junction and in the rostral hindbrain.
TS15: branchial arch Present 1G
TS15: limb Strong 1G

Specimen 1K: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forebrain Present Regionally restricted 1K Expression is dorsal.
TS17: hindbrain Present Regionally restricted 1K Expression is at the midbrain/hindbrain junction.
TS17: midbrain Present Regionally restricted 1K Expression is at the midbrain/hindbrain junction.
TS17: branchial arch Present 1K
TS17: limb Strong 1K

Specimen 2B: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future forebrain Present Regionally restricted 2B Expression is dorsal.
TS15: future hindbrain Present Regionally restricted 2B Expression is at the midbrain/hindbrain junction.
TS15: future midbrain Present Regionally restricted 2B Expression is at the midbrain/hindbrain junction.

Specimen 2F: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: branchial arch Present Regionally restricted 2F Expreion is in the pharyngeal endoderm.
TS15: pharynx epithelium Present 2F

Specimen 2J: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: lung Present 2J

Specimen 3B: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forelimb bud apical ectodermal ridge Strong 3B
TS17: forelimb bud mesenchyme Strong Regionally restricted 3B Expression is in mesenchymal cells in the proximal region.

Specimen 3F: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forelimb bud apical ectodermal ridge Strong 3F
TS17: forelimb bud mesenchyme Strong Regionally restricted 3F Expression is in mesenchymal cells in the proximal region.

Specimen 3J: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: hand Present 3J Expression is in the apical ectodermal ridge.

Specimen 3N: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: foot Present Regionally restricted 3N Expression is in the apical ectodermal ridge.

Specimen 4B: embryonic day 15.5 (more )
Note: Bell stage tooth.
Structure Level Pattern Image Note
TS23: dental papilla Present 4B

Specimen 4F: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: facial bone primordium Present Regionally restricted 4F Expression is in the cartilage primordium.
TS23: turbinate bone primordium Present Regionally restricted 4F Expression is in the cartilage primordium.

Specimen 4J: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: lung mesenchyme Present 4J

Specimen 4N: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: pineal primordium Present Regionally restricted 4N Expression is in the dorsal primordium.

Specimen 4R: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: forebrain Present Regionally restricted 4R Expression is in the hippocampus.

Specimen 4V: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: humerus Present Regionally restricted 4V Expression is in the prehypertrophic and hypertrophic chondrocytes of long bones.

Specimen Table 1 E12.5: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: forebrain Moderate Regionally restricted Expression is in the hippocampus.
TS20: lung Moderate
TS20: tongue Moderate

Specimen Table 1 E15.5: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: forebrain Strong Regionally restricted Expression is in the hippocampus.
TS23: cranium Moderate
TS23: facial bone primordium Moderate
TS23: lung Moderate
TS23: skeleton Moderate Regionally restricted Expression is in the long bones.
TS23: pineal primordium Weak
TS23: spinal cord Weak
TS23: tongue Weak
TS23: tooth Weak
TS23: vertebra Weak

Specimen Table 1 E17.5: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: tooth Strong
TS25: skeleton Moderate Regionally restricted Expression is in the long bones.
TS25: cranium Moderate
TS25: facial bone Moderate
TS25: vertebra Moderate
TS25: forebrain Weak Regionally restricted Expression is in the hippocampus.
TS25: lung Weak
TS25: pineal gland Weak
TS25: spinal cord Weak

Specimen Not shown: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: palatal shelf Present
TS23: thalamus Present Regionally restricted Expression is in the ventral thalamus.

Specimen Not shown: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: 1st branchial arch Present Regionally restricted Expression is in the peripheral mesenchymal cells immediately underneath the surface ectoderm.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory