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Gene Expression Data
Assay Details
Assay
Reference: J:85283 Marijanovic Z, et al., Closing the gap: identification of human 3-ketosteroid reductase, the last unknown enzyme of mammalian cholesterol biosynthesis. Mol Endocrinol. 2003 Sep;17(9):1715-25
Assay type: RNA in situ
MGI Accession ID: MGI:3663117
Gene symbol: Hmgcr
Gene name: 3-hydroxy-3-methylglutaryl-Coenzyme A reductase
Probe: HMG-CoA cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 6B: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: embryo Moderate 6B Ubiquitous expression.
TS17: dorsal root ganglion Strong 6B
TS17: trigeminal ganglion Strong 6B
TS17: forelimb bud Strong Regionally restricted 6B Expression is in the distal tip of the forelimb buds.
Specimen 6D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: 2nd branchial arch Present 6D Expression is at the anterior margin.
TS17: 3rd branchial arch Present 6D Expression is at the posterior margin.
Specimen 6F: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: central nervous system ganglion Strong 6F
TS19: dorsal root ganglion Strong 6F
TS19: neural tube Strong 6F
Specimen 6H: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: central nervous system ganglion Strong 6H Expression is in Froriep's ganglia.
Specimen 6J: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: foot mesenchyme Present 6J
TS20: hand mesenchyme Present 6J
Specimen 6L: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: limb interdigital region Present 6L
Specimen Not Shown: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: cranial ganglion Strong
TS19: tail Strong
Specimen Not Shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cranial ganglion Strong
Specimen 7Hmgcr: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: vibrissa Present Regionally restricted 7_Hmgcr Expression is absent in the centers of the follicles.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory