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Gene Expression Data
Assay Details
Assay
Reference: J:86959 Baxter LL, et al., Pmel17 expression is Mitf-dependent and reveals cranial melanoblast migration during murine development. Gene Expr Patterns. 2003 Dec;3(6):703-7
Assay type: RNA in situ
MGI Accession ID: MGI:3028556
Gene symbol: Pmel
Gene name: premelanosome protein
Probe: Pmel17 probe
Probe preparation: Antisense
Results
Specimen 1A: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: optic vesicle Strong Regionally restricted 1A Expression is at the dorsal edge, the presumptive RPE. Higher magnification was shown in the inset.
Specimen 1B: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: optic cup outer layer Strong 1B
TS17: surface ectoderm Strong Regionally restricted 1B Expression is in melanoblasts in the head and along the length of the embryo.
Specimen 1C: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: pigmented retinal epithelium Strong 1C
TS19: surface ectoderm Strong Regionally restricted 1C Expression is in melanoblasts along the rostral caudal axis.
Specimen 1D: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: pigmented retinal epithelium Strong 1D
TS20: skin Strong Regionally restricted 1D Expression is in melanoblasts along the rostral caudal axis.
Specimen 1E: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: surface ectoderm Strong Regionally restricted 1E Expression is shown in melanoblasts along the dorsal surface of the tail caudal to the hindlimbs.
Specimen Not Shown: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: pigmented retinal epithelium Present
Specimen 2A: embryonic day 10.5 (more )
Note: 35-37 somites.
Structure Level Pattern Image Note
TS17: surface ectoderm Strong Regionally restricted 2A Expression is in melanoblasts at the dorsal surface of the midbrain-hindbrain boundary.
Specimen 2B: embryonic day 10.5 (more )
Note: 35-37 somites.
Structure Level Pattern Image Note
TS17: surface ectoderm Strong Regionally restricted 2B Expression is in melanoblasts at the dorsal surface of the midbrain-hindbrain boundary and in cells extending from this region laterally and towards the developing eye.
Specimen 2C: embryonic day 10.5 (more )
Note: 35-37 somites.
Structure Level Pattern Image Note
TS17: surface ectoderm Strong Regionally restricted 2C Expression is in melanoblasts at the dorsal surface of the midbrain-hindbrain boundary and in cells extending from this region laterally and towards the developing eye.
Specimen 3: embryonic day 11.5 (more )
Note: Double labeled: orange/red - Pmel; blue - Dct (assay MGI:3028557).
Structure Level Pattern Image Note
TS19: surface ectoderm Strong Single cells 3 Shown is expression in cells in a cervical region. There is exclusive expression closer to the dorsal surface, other cells also expressed Dct. Higher magnification was shown in the inset.
Specimen 4A: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: pigmented retinal epithelium Strong 4A
TS19: surface ectoderm Strong Single cells 4A Expression is in melanoblasts.
Specimen 4C: embryonic day 11.5; MitfMi/MitfMi (more )
Structure Level Pattern Image Note
TS19: pigmented retinal epithelium Absent 4C
TS19: surface ectoderm Absent 4C
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory