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Gene Expression Data
Assay Details
Assay
Reference: J:82803 Dabdoub A, et al., Wnt signaling mediates reorientation of outer hair cell stereociliary bundles in the mammalian cochlea. Development. 2003 Jun;130(11):2375-84
Assay type: RNA in situ
MGI Accession ID: MGI:2655282
Gene symbol: Wnt7a
Gene name: wingless-type MMTV integration site family, member 7A
Probe: Wnt7a probe3
Probe preparation: Antisense
Results
Specimen 6A: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: cochlea Present Regionally restricted 6A Expression is present in the basal region of the cochlea.
TS22: cochlear duct Present Regionally restricted 6A The expression spans most of the width of the floor of the duct in the apical turn of the cochlea.

Specimen 6B: embryonic day 14.0 (more )
Note: This is a cross section through the apical turn of the cochlea.
Structure Level Pattern Image Note
TS22: cochlear duct epithelium Present Regionally restricted 6B There is broad expression in the inner half of the epithelium. However, there is a dintinct boundary of expression that correlates with the spiral vessel, an embryonic marker for the location of the developing organ of Corti.

Specimen 6C: embryonic day 14.0 (more )
Note: This is a cross section through the basal region of the cochlear duct.
Structure Level Pattern Image Note
TS22: cochlear duct Present Regionally restricted 6C Expression is present in a band of cells that extends from the boundary of the spiral vessel towards the inner side of the duct, as well as in some cells located at the inner edge of the duct.

Specimen 6D: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: cochlea Strong Regionally restricted 6D Expression is present in a narrow band of cells that extends along the length of the cochlea from base to apex; it is probably the developing sensory epithelium.
TS24: cochlear duct Weak Regionally restricted 6D Weak expression is present in some cells in the apical region of the inner half of the cochlear duct.

Specimen 6E: embryonic day 16.0 (more )
Note: This is a cross section through the basal region of the cochlear duct.
Structure Level Pattern Image Note
TS24: cochlear duct Strong Regionally restricted 6E Expression is present in the developing pillar cells located directly above the spiral vessel, an embryonic marker of the location of the developing organ of Corti.

Specimen 6F: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: inner ear epithelium Present Regionally restricted 6F Expression is present in the inner and outer pillar cells, with the possibility of a small amount of expression in the Deiter's cell located underneath the first row of outer hair cells.

Specimen P3: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: inner ear Present Regionally restricted Expression is present in the pillar cells.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory