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Gene Expression Data
Assay Details
Assay
Reference: J:36835 Monkley SJ, et al., Targeted disruption of the Wnt2 gene results in placentation defects. Development. 1996 Nov;122(11):3343-53
Assay type: RNA in situ
MGI Accession ID: MGI:2447733
Gene symbol: Wnt2
Gene name: wingless-type MMTV integration site family, member 2
Probe: Wnt2 cDNA2
Probe preparation: Antisense labelled with digoxigenin RNA
Assay notes: The molecular probe (MGI:2447724) gave identical results.
Results
Specimen 1A: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: heart Present Regionally restricted 1A Expression was detected in the precardiac mesoderm.

Specimen 1B: embryonic day 7.75 (more )
Structure Level Pattern Image Note
TS12: heart Present Regionally restricted 1B Expression was detected in the mesoderm.

Specimen 1C: embryonic day 8.0 (more )
Structure Level Pattern Image Note
TS12: allantois Weak 1C
TS12: heart Present Graded 1C Expression was detected in a crescent shape in the heart mesoderm with weakest expression in the differentiating myocardial and endocardial cells and strongest expression in the lateral arms of the crescent.

Specimen 1D: embryonic day 7.75 (more )
Note: The plane of section was transverse.
Structure Level Pattern Image Note
TS12: splanchnopleure Present 1D
TS12: heart Present Graded 1D Expression was detected in a crescent shape in the heart field mesoderm with strongest expression in the lateral arms of the crescent - the prospective sinus venosus - and weaker in the more medial myocardial cells.
TS12: sinus venosus Strong 1D

Specimen 1E: embryonic day 8.0 (more )
Note: The plane of section was transverse.
Structure Level Pattern Image Note
TS12: splanchnopleure Present 1E
TS12: heart Present Graded 1E Expression was detected in a crescent shape in the heart field mesoderm with strongest expression in the lateral arms of the crescent - the prospective sinus venosus - and weaker in the more medial myocardial cells.
TS12: sinus venosus Strong 1E

Specimen 2A: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: extraembryonic component Present Regionally restricted 2A Expression was detected in the allantois and the chorioallantoic plate.
TS13: heart Weak 2A
TS13: septum transversum Present 2A
TS13: sinus venosus Present 2A

Specimen 2B: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: extraembryonic component Present Regionally restricted 2B Expression was detected in the chorioallantoic plate.
TS15: heart Weak 2B
TS15: septum transversum Present 2B
TS15: sinus venosus Present 2B

Specimen 2C: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: extraembryonic component Present Regionally restricted 2C Expression was detected in the chorioallantoic plate.
TS17: heart Weak 2C
TS17: septum transversum Present 2C
TS17: sinus venosus Present 2C

Specimen 2D: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: extraembryonic component Present Regionally restricted 2D Expression was detected in the blood vessels but was absent in the trophoblasts.
TS28: placenta Present Regionally restricted 2D Expression was detected in the blood vessels but was absent in the trophoblasts.

Specimen 2E: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: extraembryonic component Present Regionally restricted 2E Expression was detected in the blood vessels but was absent in the trophoblasts.
TS28: placenta Present Regionally restricted 2E Expression was detected in the blood vessels but was absent in the trophoblasts.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory