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pOtd9 Probe Detail
Nucleotide
Probe/Clone
  • Name
    pOtd9
  • Sequence Type
    cDNA
  • ID
    MGI:23226
  • Region Covered
    includes 3' portion of coding region and homeodomain
  • Vector Type
    Plasmid
  • Insert Site
    EcoRI
  • Insert Size
    1.0kb
  • Synonyms
    pBSOtd9
Source
  • Species
    mouse, laboratory
  • Age
    embryonic day 8.5
  • Tissue
    embryo
Genes
Otx2 orthodenticle homeobox 2
Expression
  • Assay Results
    146
References
J:20959 Ang SL, et al., Positive and negative signals from mesoderm regulate the expression of mouse Otx2 in ectoderm explants. Development. 1994 Oct;120(10):2979-89
J:38388 Dupe V, et al., In vivo functional analysis of the Hoxa-1 3' retinoic acid response element (3'RARE). Development. 1997 Jan;124(2):399-410
J:41809 Filosa S, et al., goosecoid and HNF-3 beta genetically interact to regulate neural tube patterning during mouse embryogenesis. Development. 1997 JUL;124(14):2843-2854
J:46973 Studer M, et al., Genetic interactions between Hoxa1 and Hoxb1 reveal new roles in regulation of early hindbrain patterning. Development. 1998 Mar;125(6):1025-36
J:42219 Shawlot W, et al., Lim1 is required in both primitive streak-derived tissues and visceral endoderm for head formation in the mouse. Development. 1999 Nov;126(22):4925-32
J:53656 Perea-Gomez A, et al., HNF3beta and Lim1 interact in the visceral endoderm to regulate primitive streak formation and anterior-posterior polarity in the mouse embryo. Development. 1999 Oct;126(20):4499-511
J:57262 Song J, et al., The type II activin receptors are essential for egg cylinder growth, gastrulation, and rostral head development in mice. Dev Biol. 1999 Sep 1;213(1):157-69
J:73067 Li JY, et al., Otx2 and Gbx2 are required for refinement and not induction of mid-hindbrain gene expression. Development. 2001 Dec;128(24):4979-91
J:77125 Norris DP, et al., The Foxh1-dependent autoregulatory enhancer controls the level of Nodal signals in the mouse embryo. Development. 2002 Jul;129(14):3455-68
J:88939 Rhinn M, et al., Isolation and expression of the homeobox gene Gbx1 during mouse development. Dev Dyn. 2004 Feb;229(2):334-9
J:93140 Lu CC, et al., Multiple roles for Nodal in the epiblast of the mouse embryo in the establishment of anterior-posterior patterning. Dev Biol. 2004 Sep 1;273(1):149-59
J:93571 Rowan S, et al., Transdifferentiation of the retina into pigmented cells in ocular retardation mice defines a new function of the homeodomain gene Chx10. Development. 2004 Oct;131(20):5139-52
J:106405 Mackay DR, et al., The mouse Ovol2 gene is required for cranial neural tube development. Dev Biol. 2006 Mar 1;291(1):38-52
J:173623 Biechele S, et al., Porcupine homolog is required for canonical Wnt signaling and gastrulation in mouse embryos. Dev Biol. 2011 Jul 15;355(2):275-85
J:178972 Cajal M, et al., Clonal and molecular analysis of the prospective anterior neural boundary in the mouse embryo. Development. 2012 Jan;139(2):423-36
J:226614 Costello I, et al., Lhx1 functions together with Otx2, Foxa2, and Ldb1 to govern anterior mesendoderm, node, and midline development. Genes Dev. 2015 Oct 15;29(20):2108-22
J:236404 Minocha S, et al., Epiblast-specific loss of HCF-1 leads to failure in anterior-posterior axis specification. Dev Biol. 2016 Oct 1;418(1):75-88
J:238567 Houtmeyers R, et al., Zic2 mutation causes holoprosencephaly via disruption of NODAL signalling. Hum Mol Genet. 2016 Sep 15;25(18):3946-3959

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory