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Gene Expression Data
Assay Details
Assay
Reference: J:77125 Norris DP, et al., The Foxh1-dependent autoregulatory enhancer controls the level of Nodal signals in the mouse embryo. Development. 2002 Jul;129(14):3455-68
Assay type: RNA in situ
MGI Accession ID: MGI:2183484
Gene symbol: Foxa2
Gene name: forkhead box A2
Probe: Hnf3b probe7
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 2E (to): embryonic day 6.5 (more )
Structure Level Pattern Image Note
TS10: extraembryonic visceral endoderm Present Regionally restricted 2E (top) Expression is anterior.
TS10: primitive streak Present Regionally restricted 2E (top) Expression is anterior.

Specimen 2E (bottom): embryonic day 6.5; Nodaltm1.1Rob/Nodaltm2Rob (more )
Structure Level Pattern Image Note
TS9: embryo ectoderm Present 2E (bottom)
TS9: extraembryonic visceral endoderm Present Regionally restricted 2E (bottom) Expression is distal.

Specimen 4J wt: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: node Present 4J wt
TS11: primitive streak Present Regionally restricted 4J wt Expression is in the midline.
TS11: definitive endoderm Present Regionally restricted 4J wt Expression is anterior.

Specimen 4J delta600/-: embryonic day 7.5; Nodaltm1.1Rob/Nodaltm2Rob (more )
Structure Level Pattern Image Note
TS11: node Trace 4J delta600/-
TS11: primitive streak Trace Regionally restricted 4J delta600/- Expression is in the midline.
TS11: definitive endoderm Trace Regionally restricted 4J delta600/- Expression is anterior.

Specimen 4K wt: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: neural ectoderm Present Regionally restricted 4K wt Expression in the CNS and the definitive endoderm extends into the area of the ventral forebrain.
TS13: trunk Present Regionally restricted 4K wt Expression in the CNS and the definitive endoderm extends into the area of the ventral forebrain.

Specimen 4K delta600/-: embryonic day 8.5; Nodaltm1.1Rob/Nodaltm2Rob (more )
Structure Level Pattern Image Note
TS13: neural ectoderm Present Regionally restricted 4K delta600/- In this mutant the expression does not extend as anteriorly as in wild-type embryos. Expression is limited to the level of the heart.
TS13: trunk Present Regionally restricted 4K delta600/- In this mutant the expression does not extend as anteriorly as in wild-type embryos. Expression is limited to the level of the heart.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory