Gene Expression Data
Assay Details
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Assay
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Reference:
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J:75946
Kanai-Azuma M, et al., Depletion of definitive gut endoderm in Sox17-null mutant mice. Development. 2002 May;129(10):2367-79
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:2180032
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Gene symbol:
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Foxa1
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Gene name:
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forkhead box A1
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Probe:
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c24
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Probe preparation:
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Antisense RNA
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Results
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Specimen
4A +/- fg:
embryonic day 8.5; Sox17tm1Ysk/Sox17 +
(more  )
Specimen
4A +/- fg:
(close  )
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Genetic Background:
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involves: 129S1/Sv
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Mutant Allele(s):
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Sox17tm1Ysk/Sox17+
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Age:
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embryonic day 8.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference. Theiler stage of this specimen assigned by curators from EMAGE.
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
4A -/- fg:
(close )
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Genetic Background:
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involves: 129S1/Sv
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Mutant Allele(s):
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Sox17tm1Ysk/Sox17tm1Ysk
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Age:
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embryonic day 8.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS13: gut endoderm |
Present |
Regionally restricted |
4A -/- fg
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Relative to that seen in wild-type embryos, expression in mutant embryos is confined to a much narrower medial and paraxial domain along the entire anterior-posterior axis in the embryonic gut.
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Specimen
4A +/- hg:
embryonic day 8.5; Sox17tm1Ysk/Sox17 +
(more )
Specimen
4A +/- hg:
(close )
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Genetic Background:
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involves: 129S1/Sv
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Mutant Allele(s):
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Sox17tm1Ysk/Sox17+
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Age:
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embryonic day 8.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
4A -/- hg:
(close )
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Genetic Background:
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involves: 129S1/Sv
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Mutant Allele(s):
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Sox17tm1Ysk/Sox17tm1Ysk
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Age:
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embryonic day 8.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS12: gut endoderm |
Present |
Regionally restricted |
4A -/- hg
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Relative to that seen in wild-type embryos, expression in mutant embryos is confined to a much narrower medial and paraxial domain along the entire anterior-posterior axis in the embryonic gut.
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Specimen
4B +/-:
embryonic day 9.5; Sox17tm1Ysk/Sox17 +
(more )
Specimen
4B +/-:
(close )
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Genetic Background:
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involves: 129S1/Sv
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Mutant Allele(s):
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Sox17tm1Ysk/Sox17+
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Age:
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embryonic day 9.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference. Theiler stage of this specimen assigned by curators from EMAGE.
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS14: gut |
Present |
Regionally restricted |
4B +/-
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Expression is present in the gut endoderm.
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Specimen
4B -/-:
(close )
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Genetic Background:
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involves: 129S1/Sv
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Mutant Allele(s):
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Sox17tm1Ysk/Sox17tm1Ysk
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Age:
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embryonic day 9.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: gut |
Present |
Regionally restricted |
4B -/-
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Relative to that seen in wild-type embryos, expression in the gut endoderm of mutant embryos is confined to a much narrower medial and paraxial domain along the entire anterior-posterior axis in the embryonic gut.
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Specimen
4C +/-:
embryonic day 8.5; Sox17tm1Ysk/Sox17 +
(more )
Specimen
4C +/-:
(close )
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Genetic Background:
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involves: 129S1/Sv
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Mutant Allele(s):
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Sox17tm1Ysk/Sox17+
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Age:
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embryonic day 8.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference. Theiler stage of this specimen assigned by curators from EMAGE.
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Sex:
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Not Specified
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Type:
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section
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Specimen
4C -/-:
(close )
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Genetic Background:
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involves: 129S1/Sv
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Mutant Allele(s):
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Sox17tm1Ysk/Sox17tm1Ysk
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Age:
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embryonic day 8.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS13: gut endoderm |
Present |
Regionally restricted |
4C -/-
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Relative to that seen in wild-type embryos, expression in mutant embryos is confined to a much narrower medial and paraxial domain along the entire anterior-posterior axis in the embryonic gut.
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Specimen
4D +/-:
embryonic day 9.5; Sox17tm1Ysk/Sox17 +
(more )
Specimen
4D +/-:
(close )
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Genetic Background:
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involves: 129S1/Sv
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Mutant Allele(s):
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Sox17tm1Ysk/Sox17+
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Age:
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embryonic day 9.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: gut |
Present |
Regionally restricted |
4D +/-
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Expression is present in the gut endoderm.
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Specimen
4D -/-:
(close )
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Genetic Background:
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involves: 129S1/Sv
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Mutant Allele(s):
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Sox17tm1Ysk/Sox17tm1Ysk
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Age:
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embryonic day 9.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: gut |
Present |
Regionally restricted |
4D -/-
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Relative to that seen in wild-type embryos, expression in the gut endoderm of mutant embryos is confined to a much narrower medial and paraxial domain along the entire anterior-posterior axis in the embryonic gut.
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Specimen
Not shown -/+:
embryonic day 8.5; Sox17tm1Ysk/Sox17 +
(more )
Note: The authors defined normal embryos as being either wild-type or heterozygous, so for this study, they could have used a wild-type embryo.
Specimen
Not shown -/+:
(close )
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Genetic Background:
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involves: 129S1/Sv
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Mutant Allele(s):
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Sox17tm1Ysk/Sox17+
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Age:
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embryonic day 8.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Note:
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The authors defined normal embryos as being either wild-type or heterozygous, so for this study, they could have used a wild-type embryo.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS13: gut endoderm |
Present |
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Expression is present in the anterior and posterior endoderm of the gut.
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Specimen
Not shown -/-:
(close )
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Genetic Background:
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involves: 129S1/Sv
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Mutant Allele(s):
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Sox17tm1Ysk/Sox17tm1Ysk
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Age:
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embryonic day 8.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS13: gut endoderm |
Present |
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Expression is present in the anterior and posterior endoderm of the gut, but its level is significantly reduced relative to that seen in wild type embryos.
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Analysis Tools