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Gene Expression Data
Assay Details
Assay
Reference: J:75954 Dunwoodie SL, et al., Axial skeletal defects caused by mutation in the spondylocostal dysplasia/pudgy gene Dll3 are associated with disruption of the segmentation clock within the presomitic mesoderm. Development. 2002 Apr;129(7):1795-806
Assay type: Immunohistochemistry
MGI Accession ID: MGI:2178632
Gene symbol: Nefm
Gene name: neurofilament, medium polypeptide
Antibody: anti-neurofilament clone 2H3
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 4A: embryonic day 10.5; Dll3tm1Rbe/Dll3+ (more )
Structure Level Pattern Image Note
TS17: peripheral nervous system Present 4A Authors report a regular periodicity with which spinal nerves and ganglia form.
TS17: spinal ganglion Present 4A Authors report a regular periodicity with which spinal nerves and ganglia form.
TS17: dorsal root ganglion Present 4A Authors report a regular periodicity with which spinal nerves and ganglia form.
TS17: spinal nerve Present 4A Authors report a regular periodicity with which spinal nerves and ganglia form.

Specimen 4B: embryonic day 10.5; Dll3tm1Rbe/Dll3+ (more )
Structure Level Pattern Image Note
TS17: segmental spinal nerve Present 4B Ventral spinal axons pass through anterior of somite segments.

Specimen 4F: embryonic day 10.5; Dll3tm1Rbe/Dll3+ (more )
Structure Level Pattern Image Note
TS17: tail neural tube Present 4F

Specimen 4C: embryonic day 10.5; Dll3tm1Rbe/Dll3tm1Rbe (more )
Structure Level Pattern Image Note
TS17: peripheral nervous system Present 4C Spinal ganglia and axons are unevenly spaced.
TS17: spinal ganglion Present 4C Spinal ganglia and axons are unevenly spaced.
TS17: dorsal root ganglion Present 4C Spinal ganglia and axons are unevenly spaced.
TS17: spinal nerve Present 4C Spinal ganglia and axons are unevenly spaced.

Specimen 4D: embryonic day 10.5; Dll3tm1Rbe/Dll3tm1Rbe (more )
Structure Level Pattern Image Note
TS17: segmental spinal nerve Present 4D Spinal axons pass through anterior, posterior or central part of somite segments.

Specimen 4G: embryonic day 10.5; Dll3tm1Rbe/Dll3tm1Rbe (more )
Structure Level Pattern Image Note
TS17: tail neural tube Present 4G Authors report that the neural tube is "kinked."

Specimen 4E: embryonic day 11.5; Dll3tm1Rbe/Dll3tm1Rbe (more )
Structure Level Pattern Image Note
TS19: peripheral nervous system Present 4E Spinal ganglia and axons are unevenly spaced.
TS19: spinal ganglion Present 4E Spinal ganglia and axons are unevenly spaced.
TS19: spinal nerve Present 4E Spinal ganglia and axons are unevenly spaced.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory