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Gene Expression Data
Assay Details
Assay
Reference: J:73527 Ferguson CA, et al., The role of effectors of the activin signalling pathway, activin receptors IIA and IIB, and Smad2, in patterning of tooth development. Development. 2001 Nov;128(22):4605-13
Assay type: RNA in situ
MGI Accession ID: MGI:2157142
Gene symbol: Irx1
Gene name: Iroquois homeobox 1
Probe: Irx1 cDNA6
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 1. F., G.: embryonic day 11.0 (more )
Note: 1. F. is a brightfield image of G.
Structure Level Pattern Image Note
TS18: oral epithelium Present Regionally restricted 1G , 1F Expression is detected in the dental epithelia of the molars.
Specimen 1. J.: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: oral epithelium Present Regionally restricted 1J Expression is detected in the dental epithelia of the incisors.
Specimen 1. L.: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: lower jaw molar Present 1L
TS21: upper jaw molar Present 1L
Specimen 1. M.: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: lower jaw molar Present 1M
TS22: upper jaw molar Present 1M
Specimen 2. A.: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: lower jaw incisor epithelium Present 2A
TS21: upper jaw incisor epithelium Present 2A
TS21: dermis Present Regionally restricted 2A Expression is detected in the cephalic mesenchyme around the optic vesicle and the superficial dermis of the skin.
TS21: embryo mesenchyme Present Regionally restricted 2A Expression is detected in the cephalic mesenchyme around the optic vesicle and the superficial dermis of the skin.
Specimen 2. B, C.: embryonic day 13.5; Inhbatm1Zuk/Inhbatm1Zuk (more )
Note: 2. C. is a brightfield image of B.
Structure Level Pattern Image Note
TS21: lower jaw incisor epithelium Absent 2B , 2C
TS21: upper jaw incisor epithelium Absent 2B , 2C
TS21: dermis Present Regionally restricted 2C , 2B Expression is detected in the cephalic mesenchyme around the optic vesicle and the superficial dermis of the skin.
TS21: embryo mesenchyme Present Regionally restricted 2C , 2B Expression is detected in the cephalic mesenchyme around the optic vesicle and the superficial dermis of the skin.
Specimen 2. E.: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: lower jaw molar epithelium Present 2E
TS22: upper jaw molar epithelium Present 2E
TS22: dermis Present Regionally restricted 2E Expression is detected in the cephalic mesenchyme around the optic vesicle and the superficial dermis of the skin.
TS22: embryo mesenchyme Present Regionally restricted 2E Expression is detected in the cephalic mesenchyme around the optic vesicle and the superficial dermis of the skin.
Specimen 2. F., G.: embryonic day 14.5; Inhbatm1Zuk/Inhbatm1Zuk (more )
Note: 2. G. is a brightfield image of F.
Structure Level Pattern Image Note
TS22: lower jaw molar epithelium Absent 2G , 2F
TS22: upper jaw molar epithelium Absent 2G , 2F
TS22: dermis Present Regionally restricted 2G , 2F Expression is detected in the cephalic mesenchyme around the optic vesicle and the superficial dermis of the skin.
TS22: embryo mesenchyme Present Regionally restricted 2G , 2F Expression is detected in the cephalic mesenchyme around the optic vesicle and the superficial dermis of the skin.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory