About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:43309 Meyer D, et al., Isoform-specific expression and function of neuregulin. Development. 1997 Sep;124(18):3575-86
Assay type: RNA in situ
MGI Accession ID: MGI:2155297
Gene symbol: Erbb3
Gene name: erb-b2 receptor tyrosine kinase 3
Probe: ErbB3 cDNA2
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 5D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: central nervous system Present Regionally restricted 5D Expression in the Schwann cell precursors that line the cranial nerves.

Specimen 5E: embryonic day 10.5; Nrg1tm2Cbm/Nrg1tm2Cbm (more )
Structure Level Pattern Image Note
TS17: central nervous system Absent 5E Absence of expression due to the absence of the Schwann cell precursors that line the cranial nerves.

Specimen 5F: embryonic day 10.5; Nrg1tm1Leth/Nrg1tm1Leth (more )
Structure Level Pattern Image Note
TS17: central nervous system Present Regionally restricted 5F Expression in the Schwann cell precursors that line the cranial nerves.

Specimen 5G: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: central nervous system Present 5G Expression in the Schwann cell precursors that line the cranial nerves.

Specimen 5H: embryonic day 10.5; Nrg1tm2Cbm/Nrg1tm2Cbm (more )
Structure Level Pattern Image Note
TS17: central nervous system Absent 5H Absence of expression due to the absence of the Schwann cell precursors that line the cranial nerves.

Specimen 5I: embryonic day 10.5; Nrg1tm1Leth/Nrg1tm1Leth (more )
Structure Level Pattern Image Note
TS17: central nervous system Present 5I Expression in the Schwann cell precursors that line the cranial nerves.

Specimen 6A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: peripheral nervous system Present 6A Expression in the Schwann cell precursors that line the spinal nerves in the trunk.

Specimen 6B: embryonic day 10.5; Nrg1tm2Cbm/Nrg1tm2Cbm (more )
Structure Level Pattern Image Note
TS17: peripheral nervous system Present 6B Reduced expression in the Schwann cell precursors that line the spinal nerves in the trunk due to the reduced number of cells.

Specimen 6C: embryonic day 10.5; Nrg1tm1Leth/Nrg1tm1Leth (more )
Structure Level Pattern Image Note
TS17: peripheral nervous system Present 6C Expression in the Schwann cell precursors that line the spinal nerves in the trunk.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
05/07/2024
MGI 6.23
The Jackson Laboratory