Gene Expression Data
Assay Details
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Assay
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Reference:
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J:73069
Wang W, et al., Hmx2 homeobox gene control of murine vestibular morphogenesis. Development. 2001 Dec;128(24):5017-29
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:2155123
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Gene symbol:
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Dlx5
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Gene name:
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distal-less homeobox 5
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Probe:
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Dlx5 probe2
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Probe preparation:
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Antisense labelled with S35 RNA
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Visualized with:
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Autoradiography
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Results
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Specimen
Not shown, +/+:
embryonic day 10.5
(more  )
Specimen
Not shown, +/+:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 10.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
Not shown, Hmx2-/-:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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Mutant Allele(s):
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Hmx2tm1Tlu/Hmx2tm1Tlu
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Age:
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embryonic day 10.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: otocyst |
Present |
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The expression pattern is the same as in wild-type embryos.
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Specimen
7C:
embryonic day 11.5
(more )
Specimen
7C:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 11.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: endolymphatic appendage |
Present |
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7C
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Expression is present in the developing endolymphatic sac.
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| TS19: inner ear |
Present |
Regionally restricted |
7C
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Expression is present in discrete patches in the epithelium located in the anterior portion of the lateral aspect of the otic vesicle. There is also expression in the posterior otic vesicle.
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Specimen
7D:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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Mutant Allele(s):
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Hmx2tm1Tlu/Hmx2tm1Tlu
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Age:
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embryonic day 11.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: inner ear |
Present |
Regionally restricted |
7D
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There is ectopic expression in the presumptive fusion plate. There are no longer discrete patches of expression in the epithelium, as in wild type; instead the gap between the rostral and caudal expression domains is filled with expressing cells.
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Analysis Tools