Gene Expression Data
Assay Details
Assay
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Reference:
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J:65298
Corbin JG, et al., The gsh2 homeodomain gene controls multiple aspects of telencephalic development. Development. 2000 Dec;127(23):5007-20
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:2153164
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Gene symbol:
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Gad1
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Gene name:
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glutamate decarboxylase 1
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Probe:
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rat GAD67 probe
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Results
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Specimen
2I:
embryonic day 12.5; Gsx2tm1Ssp/Gsx2 +
(more )
Specimen
2I:
(close )
Genetic Background:
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Not Specified
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Mutant Allele(s):
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Gsx2tm1Ssp/Gsx2+
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Age:
|
embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
2J:
(close )
Genetic Background:
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Not Specified
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Mutant Allele(s):
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Gsx2tm1Ssp/Gsx2tm1Ssp
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Age:
|
embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
3I:
embryonic day 15.5; Gsx2tm1Ssp/Gsx2 +
(more )
Specimen
3I:
(close )
Genetic Background:
|
Not Specified
|
Mutant Allele(s):
|
Gsx2tm1Ssp/Gsx2+
|
Age:
|
embryonic day 15.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
3J:
(close )
Genetic Background:
|
Not Specified
|
Mutant Allele(s):
|
Gsx2tm1Ssp/Gsx2tm1Ssp
|
Age:
|
embryonic day 15.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS23: telencephalon |
Present |
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3J
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Authors report that expression is still reduced compared with controls.
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TS23: corpus striatum |
Present |
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3J
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Significant recovery of expression in the striatal subventricular zone and mantle.
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Specimen
7C:
embryonic day 15.5; Gsx2tm1Ssp/Gsx2 +
(more )
Specimen
7C:
(close )
Genetic Background:
|
Not Specified
|
Mutant Allele(s):
|
Gsx2tm1Ssp/Gsx2+
|
Age:
|
embryonic day 15.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS23: telencephalon |
Present |
Regionally restricted |
7C
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Expression in the olfactory bulb.
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Specimen
7D:
(close )
Genetic Background:
|
Not Specified
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Mutant Allele(s):
|
Gsx2tm1Ssp/Gsx2tm1Ssp
|
Age:
|
embryonic day 15.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS23: telencephalon |
Present |
Regionally restricted |
7D
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Significant reduction of expression in the granule cells layer of the olfactory bulb.
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Specimen
7G:
embryonic day 18.5
(more )
Specimen
7G:
(close )
Genetic Background:
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Not Specified
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Age:
|
embryonic day 18.5
|
Sex:
|
Not Specified
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Type:
|
section
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Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS26: telencephalon |
Present |
Regionally restricted |
7G
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Expression in the olfactory bulb.
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Specimen
7H:
(close )
Genetic Background:
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Not Specified
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Mutant Allele(s):
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Gsx2tm1Ssp/Gsx2tm1Ssp
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Age:
|
embryonic day 18.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
not shown:
(close )
Genetic Background:
|
Not Specified
|
Mutant Allele(s):
|
Gsx2tm1Ssp/Gsx2tm1Ssp
|
Age:
|
embryonic day 18.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS26: corpus striatum |
Present |
|
|
Normal levels of expression in striatum.
|
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