About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:65298 Corbin JG, et al., The gsh2 homeodomain gene controls multiple aspects of telencephalic development. Development. 2000 Dec;127(23):5007-20
Assay type: RNA in situ
MGI Accession ID: MGI:2153164
Gene symbol: Gad1
Gene name: glutamate decarboxylase 1
Probe: rat GAD67 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 2I: embryonic day 12.5; Gsx2tm1Ssp/Gsx2+ (more )
Structure Level Pattern Image Note
TS20: telencephalon Present 2I

Specimen 2J: embryonic day 12.5; Gsx2tm1Ssp/Gsx2tm1Ssp (more )
Structure Level Pattern Image Note
TS20: lateral ganglionic eminence Present Regionally restricted 2J Absence of expression in all but the ventral-most aspect.

Specimen 3I: embryonic day 15.5; Gsx2tm1Ssp/Gsx2+ (more )
Structure Level Pattern Image Note
TS23: telencephalon Present 3I

Specimen 3J: embryonic day 15.5; Gsx2tm1Ssp/Gsx2tm1Ssp (more )
Structure Level Pattern Image Note
TS23: telencephalon Present 3J Authors report that expression is still reduced compared with controls.
TS23: corpus striatum Present 3J Significant recovery of expression in the striatal subventricular zone and mantle.

Specimen 7C: embryonic day 15.5; Gsx2tm1Ssp/Gsx2+ (more )
Structure Level Pattern Image Note
TS23: telencephalon Present Regionally restricted 7C Expression in the olfactory bulb.

Specimen 7D: embryonic day 15.5; Gsx2tm1Ssp/Gsx2tm1Ssp (more )
Structure Level Pattern Image Note
TS23: telencephalon Present Regionally restricted 7D Significant reduction of expression in the granule cells layer of the olfactory bulb.

Specimen 7G: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: telencephalon Present Regionally restricted 7G Expression in the olfactory bulb.

Specimen 7H: embryonic day 18.5; Gsx2tm1Ssp/Gsx2tm1Ssp (more )
Structure Level Pattern Image Note
TS26: telencephalon Present Regionally restricted 7H

Specimen not shown: embryonic day 18.5; Gsx2tm1Ssp/Gsx2tm1Ssp (more )
Structure Level Pattern Image Note
TS26: corpus striatum Present Normal levels of expression in striatum.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
05/14/2024
MGI 6.23
The Jackson Laboratory