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Gene Expression Data
Assay Details
Assay
Reference: J:65298 Corbin JG, et al., The gsh2 homeodomain gene controls multiple aspects of telencephalic development. Development. 2000 Dec;127(23):5007-20
Assay type: RNA in situ
MGI Accession ID: MGI:2153161
Gene symbol: Dlx1
Gene name: distal-less homeobox 1
Probe: Dlx-specific probe
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 2A: embryonic day 12.5; Gsx2tm1Ssp/Gsx2+ (more )
Structure Level Pattern Image Note
TS20: telencephalon Present 2A

Specimen 2B: embryonic day 12.5; Gsx2tm1Ssp/Gsx2tm1Ssp (more )
Structure Level Pattern Image Note
TS20: lateral ganglionic eminence Present Regionally restricted 2B Absence of expression in all but the ventral-most aspect.
TS20: medial ganglionic eminence Present Regionally restricted 2B Expression was reduced in the ventricular zone of the medial ganglionic eminence.

Specimen 3A: embryonic day 15.5; Gsx2tm1Ssp/Gsx2+ (more )
Structure Level Pattern Image Note
TS23: telencephalon Present 3A

Specimen 3B: embryonic day 15.5; Gsx2tm1Ssp/Gsx2tm1Ssp (more )
Structure Level Pattern Image Note
TS23: corpus striatum Present 3B Authors report significantly recovered expression in mutant striatum.
TS23: lateral ganglionic eminence Present Regionally restricted 3B Reduced expression; no expression in the ventricular zone.

Specimen not shown: embryonic day 15.5; Gsx2tm1Ssp/Gsx2tm1Ssp (more )
Structure Level Pattern Image Note
TS23: telencephalon Present Authors report a significant reduction in the level of expression in the olfactory bulb.

Specimen not shown: embryonic day 18.5; Gsx2tm1Ssp/Gsx2tm1Ssp (more )
Structure Level Pattern Image Note
TS26: lateral ganglionic eminence Present Regionally restricted Authors report that expression in the ventricular zone and olfactory bulb appears normal.
TS26: corpus striatum Present Authors report normal levels in the striatum.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory