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Gene Expression Data
Assay Details
Assay
Reference: J:71880 Beverdam A, et al., Severe nasal clefting and abnormal embryonic apoptosis in Alx3/Alx4 double mutant mice. Development. 2001 Oct;128(20):3975-86
Assay type: RNA in situ
MGI Accession ID: MGI:2152099
Gene symbol: Pax9
Gene name: paired box 9
Results
Specimen 9G: embryonic day 10.5 (more )
Note: For control embryos either heterozygotes or wild type were used. This specimen could have been Alx3tm1Fme/+.
Structure Level Pattern Image Note
TS17: pharynx Present 9G
TS17: 1st branchial arch mandibular component Present 9G
TS17: 1st branchial arch maxillary component Present 9G
TS17: nasal process Present 9G

Specimen 9H: embryonic day 11.5 (more )
Note: For control embryos either heterozygotes or wild type were used. This specimen could have been Alx3tm1Fme/+.
Structure Level Pattern Image Note
TS20: head mesenchyme Present Regionally restricted 9H Expression laterally from the precartilage condensation in the midline of the nasal septum around the vomeronasal organs.
TS20: nose Present Regionally restricted 9H Expression laterally from the precartilage condensation in the midline of the nasal septum around the vomeronasal organs.

Specimen 9I: embryonic day 11.5 (more )
Note: For control embryos either heterozygotes or wild type were used. This specimen could have been Alx3tm1Fme/+.
Structure Level Pattern Image Note
TS20: head mesenchyme Present Regionally restricted 9I Expression around the nasal cavities.

Specimen 9J: embryonic day 10.5; Alx3tm1Hubr/Alx3tm1Hubr, Alx4lst-J/Alx4lst-J (more )
Structure Level Pattern Image Note
TS17: pharynx Present 9J Expression was the same as in control embryos.
TS17: 1st branchial arch mandibular component Present 9J Expression was the same as in control embryos.
TS17: 1st branchial arch maxillary component Present 9J Expression was the same as in control embryos.
TS17: nasal process Present 9J Expression was the same as in control embryos.

Specimen 9K: embryonic day 11.5; Alx3tm1Hubr/Alx3tm1Hubr, Alx4lst-J/Alx4lst-J (more )
Structure Level Pattern Image Note
TS19: head mesenchyme Present Regionally restricted 9K The authors state that the expression domain changes are due to the anatomical abnormalities. In the abnormal nasal septum remnants the domain is split apart but essential characteristics appear to be retained.

Specimen 9L: embryonic day 11.5; Alx3tm1Hubr/Alx3tm1Hubr, Alx4lst-J/Alx4lst-J (more )
Structure Level Pattern Image Note
TS19: head mesenchyme Present Regionally restricted 9L The authors state that the expression domain changes are due to the anatomical abnormalities. In the abnormal nasal septum remnants the domain is split apart but essential characteristics appear to be retained.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory