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Gene Expression Data
Assay Details
Assay
Reference: J:71880 Beverdam A, et al., Severe nasal clefting and abnormal embryonic apoptosis in Alx3/Alx4 double mutant mice. Development. 2001 Oct;128(20):3975-86
Assay type: RNA in situ
MGI Accession ID: MGI:2152083
Gene symbol: Fgf8
Gene name: fibroblast growth factor 8
Results
Specimen 9E: embryonic day 10.5 (more )
Note: For control embryos either heterozygotes or wild type were used. This specimen could have been Alx3tm1Fme/+.
Structure Level Pattern Image Note
TS17: oral epithelium Present Regionally restricted 9E Expression in restricted regions of the oral ectoderm of the first branchial arch.
TS17: nasal pit epithelium Present 9E
TS17: medial-nasal process ectoderm Present 9E

Specimen 9F: embryonic day 10.5; Alx3tm1Hubr/Alx3tm1Hubr, Alx4lst-J/Alx4lst-J (more )
Structure Level Pattern Image Note
TS17: oral epithelium Present Regionally restricted 9F No difference in expression compared to wild type.
TS17: nasal pit epithelium Present 9F No difference in expression compared to wild type.
TS17: medial-nasal process ectoderm Present 9F No difference in expression compared to wild type.

Specimen Not Shown: embryonic day 9.5 (more )
Note: For control embryos either heterozygotes or wild type were used. This specimen could have been Alx3tm1Fme/+.
Structure Level Pattern Image Note
TS15: oral region Present Regionally restricted Expression in restricted regions of the oral ectoderm of the first branchial arch.
TS15: nose Present Regionally restricted Expression in the ectoderm of the nasal pits and more distally in the medial nasal process ectoderm.

Specimen Not Shown: embryonic day 9.5; Alx3tm1Hubr/Alx3tm1Hubr, Alx4lst-J/Alx4lst-J (more )
Structure Level Pattern Image Note
TS15: oral region Present Regionally restricted No difference in expression compared to wild type.
TS15: nose Present No difference in expression compared to wild type.

Specimen Not Shown: embryonic day 11.5 (more )
Note: For control embryos either heterozygotes or wild type were used. This specimen could have been Alx3tm1Fme/+.
Structure Level Pattern Image Note
TS19: oral epithelium Present Regionally restricted Expression in restricted regions of the oral ectoderm of the first branchial arch.
TS19: nasal pit epithelium Present
TS19: medial-nasal process ectoderm Present

Specimen Not Shown: embryonic day 11.5; Alx3tm1Hubr/Alx3tm1Hubr, Alx4lst-J/Alx4lst-J (more )
Structure Level Pattern Image Note
TS19: oral epithelium Present Regionally restricted No difference in expression compared to wild type.
TS19: nasal pit epithelium Present No difference in expression compared to wild type.
TS19: medial-nasal process ectoderm Present No difference in expression compared to wild type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory