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Gene Expression Data
Assay Details
Assay
Reference: J:64588 Toresson H, et al., Genetic control of dorsal-ventral identity in the telencephalon: opposing roles for pax6 and gsh2. Development. 2000 Oct;127(20):4361-71
Assay type: Immunohistochemistry
MGI Accession ID: MGI:2150330
Gene symbol: Gsx2
Gene name: GS homeobox 2
Antibody: GSH2 antibody
Detection system: Secondary antibody
Results
Specimen 1A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: telencephalon ventricular layer Present 1A Expression in ventral telencephalic ventricular zone (VZ); highest level in lateral telencephalon; complementary to expression of PAX6.

Specimen 1C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: lateral ganglionic eminence Present Regionally restricted 1C Expression in progenitors in the ventricular zone; graded along the dorsal-ventral axis; highest levels in progenitor cells close to the boundary with PAX6.
TS20: medial ganglionic eminence Present Regionally restricted 1C Expression in progenitors in the ventricular zone; graded along the dorsal-ventral axis; highest levels in progenitor cells close to the boundary with PAX6.

Specimen 1E: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: telencephalon Present Regionally restricted 1E Expression of GSH2 and PAX6 marks the boundary between the LGE and cortical VZ.

Specimen 5B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: lateral ganglionic eminence Present Regionally restricted 5B Expression in progenitors in the ventricular zone; graded along the dorsal-ventral axis; highest levels in progenitor cells close to the boundary with PAX6.
TS20: medial ganglionic eminence Present Regionally restricted 5B Expression in progenitors in the ventricular zone; graded along the dorsal-ventral axis; highest levels in progenitor cells close to the boundary with PAX6.

Specimen 5F: embryonic day 12.5; Pax6Sey/Pax6Sey (more )
Structure Level Pattern Image Note
TS20: ganglionic eminence Present Regionally restricted 5F Expression expanded throughout lateral-most part of the LGE and into ventrolateral cortical VZ.
TS20: telencephalon Present Regionally restricted 5F Expression expanded throughout lateral-most part of the LGE and into ventrolateral cortical VZ.

Specimen 6C: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: telencephalon Present Regionally restricted 6C Expressed ventrally.

Specimen 6H: embryonic day 14.0; Pax6Sey/Pax6Sey (more )
Structure Level Pattern Image Note
TS22: telencephalon Present Regionally restricted 6H Ectopic expression in cortical progenitors throughout much of cortex, primarily within the VZ; expression in most of lateral cortical VZ.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory