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Gene Expression Data
Assay Details
Assay
Reference: J:71034 Boyl PP, et al., Forebrain and midbrain development requires epiblast-restricted Otx2 translational control mediated by its 3' UTR. Development. 2001 Aug;128(15):2989-3000
Assay type: RNA in situ
MGI Accession ID: MGI:2150158
Gene symbol: Fgf8
Gene name: fibroblast growth factor 8
Results
Specimen 7D wt: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: midbrain-hindbrain junction Present 7D Expression is at the midbrain/hindbrain junction and in the isthmus.

Specimen 7E Otx2 l/l: embryonic day 8.5; Otx2tm2Asim/Otx2tm2Asim (more )
Structure Level Pattern Image Note
TS13: midbrain-hindbrain junction Present 7E
TS13: future brain Present 7E There is a modest expansion of the expression domain in the mutant compared to wild type.

Specimen 7F Otx2 l/-: embryonic day 8.5; Otx2tm1Pas/Otx2tm2Asim (more )
Structure Level Pattern Image Note
TS13: future brain Present 7F The expression domain is expanded in mutants compared to wild type.

Specimen 8D wt: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: midbrain-hindbrain junction Present 8D Expression is at the midbrain/hindbrain junction and in the future isthmus.

Specimen 8E Otx2 l/l: embryonic day 10.5; Otx2tm2Asim/Otx2tm2Asim (more )
Structure Level Pattern Image Note
TS17: midbrain-hindbrain junction Present 8E
TS17: brain Present 8E The expression domain is slightly expanded in the mutant compared to wild type.

Specimen 8F Otx2 l/-: embryonic day 10.5; Otx2tm1Pas/Otx2tm2Asim (more )
Structure Level Pattern Image Note
TS17: brain Present 8F Expression is present in an expanded area in the mutant compared to wild type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory