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Gene Expression Data
Assay Details
Assay
Reference: J:71034 Boyl PP, et al., Forebrain and midbrain development requires epiblast-restricted Otx2 translational control mediated by its 3' UTR. Development. 2001 Aug;128(15):2989-3000
Assay type: RNA in situ
MGI Accession ID: MGI:2150155
Gene symbol: Gbx2
Gene name: gastrulation brain homeobox 2
Results
Specimen 6I wt: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: neural ectoderm Present 6I

Specimen 6J Otx2 l/-: embryonic day 7.5; Otx2tm1Pas/Otx2tm2Asim (more )
Structure Level Pattern Image Note
TS11: neural ectoderm Present 6J Expression in the mutant is similar to that seen in wild type.

Specimen Not shown Otx2 l/l: embryonic day 7.5; Otx2tm2Asim/Otx2tm2Asim (more )
Structure Level Pattern Image Note
TS11: neural ectoderm Present Expression in the mutant is similar to that seen in wild type.

Specimen 7G wt: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: midbrain-hindbrain junction Present 7G Expression is at the midbrain/hindbrain junction and in the isthmic primordium.

Specimen 7H Otx2 l/l: embryonic day 8.5; Otx2tm2Asim/Otx2tm2Asim (more )
Structure Level Pattern Image Note
TS13: midbrain-hindbrain junction Present 7H
TS13: future brain Present Regionally restricted 7H There is a modest expansion of the expression domain in the mutant compared to wild type.

Specimen 7I Otx2 l/-: embryonic day 8.5; Otx2tm1Pas/Otx2tm2Asim (more )
Structure Level Pattern Image Note
TS13: future brain Present Regionally restricted 7I The area of expression is expanded in the mutant compared to wild type.

Specimen 8G wt: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: midbrain-hindbrain junction Present 8G

Specimen 8H Otx2 l/l: embryonic day 10.5; Otx2tm2Asim/Otx2tm2Asim (more )
Structure Level Pattern Image Note
TS17: midbrain-hindbrain junction Present 8H
TS17: brain Present Regionally restricted 8H The area of expression is slightly expanded in the mutant compared to wild type.

Specimen 8I Otx2 l/-: embryonic day 10.5; Otx2tm1Pas/Otx2tm2Asim (more )
Structure Level Pattern Image Note
TS17: brain Present Regionally restricted 8I Expression is present in an extended area compared to that seen in wild type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory