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Gene Expression Data
Assay Details
Assay
Reference: J:71035 ten Berge D, et al., Prx1 and Prx2 are upstream regulators of sonic hedgehog and control cell proliferation during mandibular arch morphogenesis. Development. 2001 Aug;128(15):2929-38
Assay type: RNA in situ
MGI Accession ID: MGI:2150000
Gene symbol: Shh
Gene name: sonic hedgehog
Probe: Shh probe25
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 3E: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS18: oral epithelium Present Regionally restricted 3E Expression is in the lateral and medial domains.
Specimen 3J: embryonic day 10.5; Prrx1tm1Tex/Prrx1tm1Tex, Prrx2tm1Hubr/Prrx2tm1Hubr (more )
Structure Level Pattern Image Note
TS17: oral epithelium Present Regionally restricted 3J In this mutant expression in the medial domain is considerably reduced.
Specimen 4A: embryonic day 9.5 (more )
Note: 27 somite stage.
Structure Level Pattern Image Note
TS15: 1st branchial arch mandibular component Present Regionally restricted 4A
Specimen 4B: embryonic day 9.5; Prrx1tm1Tex/Prrx1tm1Tex, Prrx2tm1Hubr/Prrx2tm1Hubr (more )
Note: 26 somites.
Structure Level Pattern Image Note
TS15: 1st branchial arch mandibular component Present Regionally restricted 4B Epression in this mutant is the same as in wild-type embryos.
Specimen 4C: embryonic day 10.0 (more )
Note: 31 somites.
Structure Level Pattern Image Note
TS16: oral epithelium Present Regionally restricted 4C
Specimen 4D: embryonic day 10.0; Prrx1tm1Tex/Prrx1tm1Tex, Prrx2tm1Hubr/Prrx2tm1Hubr (more )
Note: 30 somites.
Structure Level Pattern Image Note
TS16: oral epithelium Present Regionally restricted 4D In this mutant medial expression is noticeably lower.
Specimen 4E: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: oral epithelium Present Regionally restricted 4E
Specimen 4F: embryonic day 10.5; Prrx1tm1Tex/Prrx1tm1Tex, Prrx2tm1Hubr/Prrx2tm1Hubr (more )
Structure Level Pattern Image Note
TS17: oral epithelium Present Regionally restricted 4F In this mutant expression is lower in the medial region.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory