|
Results
|
Specimen
2B:
embryonic day 10.5
(more  )
Specimen
2B:
(close  )
|
Genetic Background:
|
Not Specified
|
|
Age:
|
embryonic day 10.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
Specimen
2E:
(close )
|
Genetic Background:
|
involves: 101 * C3H
|
|
Mutant Allele(s):
|
ShhDsh/ShhDsh
|
|
Age:
|
embryonic day 10.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS17: forelimb bud mesenchyme |
Present |
Regionally restricted |
2E
|
Present in the muscle precursors; myogenesis seems to be initiated normally in these mutants.
|
Specimen
not shown:
(close )
|
Genetic Background:
|
Not Specified
|
|
Mutant Allele(s):
|
Shhtm1Chg/Shhtm1Chg
|
|
Age:
|
embryonic day 10.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS17: forelimb bud mesenchyme |
Present |
Regionally restricted |
|
Present in the muscle precursors; myogenesis seems to be initiated normally in these mutants.
|
Specimen
2H:
embryonic day 10.5
(more )
Note: This specimen was stained as a whole mount, embedded in gelatin, and cut on a vibratome.
Specimen
2H:
(close )
|
Genetic Background:
|
Not Specified
|
|
Age:
|
embryonic day 10.5
|
|
Age Note:
|
Theiler stage of this specimen assigned by curators from EMAGE.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section from whole mount
|
|
Embedding:
|
Gelatin
|
|
Note:
|
This specimen was stained as a whole mount, embedded in gelatin, and cut on a vibratome.
|
Specimen
2K:
embryonic day 10.5; ShhDsh/ ShhDsh
(more )
Note: This specimen was stained as a whole mount, embedded in gelatin, and cut on a vibratome.
Specimen
2K:
(close )
|
Genetic Background:
|
involves: 101 * C3H
|
|
Mutant Allele(s):
|
ShhDsh/ShhDsh
|
|
Age:
|
embryonic day 10.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section from whole mount
|
|
Embedding:
|
Gelatin
|
|
Note:
|
This specimen was stained as a whole mount, embedded in gelatin, and cut on a vibratome.
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS17: trunk dermomyotome |
Strong |
Regionally restricted |
2K
|
Expression is present in the hypaxial domain and absent from the epaxial domain.
|
| TS17: forelimb bud mesenchyme |
Present |
Regionally restricted |
2K
|
Present in the muscle precursors; myogenesis seems to be initiated normally in these mutants.
|
Specimen
not shown:
embryonic day 10.5; Shhtm1Chg/ Shhtm1Chg
(more )
Note: This specimen was stained as a whole mount, embedded in gelatin, and cut on a vibratome.
Specimen
not shown:
(close )
|
Genetic Background:
|
Not Specified
|
|
Mutant Allele(s):
|
Shhtm1Chg/Shhtm1Chg
|
|
Age:
|
embryonic day 10.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section from whole mount
|
|
Embedding:
|
Gelatin
|
|
Note:
|
This specimen was stained as a whole mount, embedded in gelatin, and cut on a vibratome.
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS17: trunk dermomyotome |
Strong |
Regionally restricted |
|
Expression is present in the hypaxial domain and absent from the epaxial domain.
|
| TS17: forelimb bud mesenchyme |
Present |
Regionally restricted |
|
Present in the muscle precursors; myogenesis seems to be initiated normally in these mutants.
|
Specimen
not shown:
embryonic day 9.5
(more )
Specimen
not shown:
(close )
|
Genetic Background:
|
Not Specified
|
|
Age:
|
embryonic day 9.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
Specimen
3A:
embryonic day 9.5
(more )
Note: This specimen was stained as a whole mount, embedded in gelatin, and cut on a vibratome.
Specimen
3A:
(close )
|
Genetic Background:
|
Not Specified
|
|
Age:
|
embryonic day 9.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section from whole mount
|
|
Embedding:
|
Gelatin
|
|
Note:
|
This specimen was stained as a whole mount, embedded in gelatin, and cut on a vibratome.
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS15: trunk somite |
Present |
Regionally restricted |
3A
|
Present in the epaxial domain.
|
Specimen
not shown:
embryonic day 9.5; ShhDsh/ ShhDsh
(more )
Specimen
not shown:
(close )
|
Genetic Background:
|
involves: 101 * C3H
|
|
Mutant Allele(s):
|
ShhDsh/ShhDsh
|
|
Age:
|
embryonic day 9.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS15: trunk somite |
Present |
Regionally restricted |
|
Expression is present in the epaxial domain, but it is significantly reduced from wild type. It was in the newly formed somites and those at the interlimb level (in the dorsomedial quadrant); it was virtually absent in the mature, cranial somites.
|
Specimen
3B:
embryonic day 9.5; ShhDsh/ ShhDsh
(more )
Note: This specimen was stained as a whole mount, embedded in gelatin, and cut on a vibratome.
Specimen
3B:
(close )
|
Genetic Background:
|
involves: 101 * C3H
|
|
Mutant Allele(s):
|
ShhDsh/ShhDsh
|
|
Age:
|
embryonic day 9.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section from whole mount
|
|
Embedding:
|
Gelatin
|
|
Note:
|
This specimen was stained as a whole mount, embedded in gelatin, and cut on a vibratome.
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS15: trunk somite |
Present |
Regionally restricted |
3B
|
Expression is present in the epaxial domain, but it is reduced compared to wild type.
|
Specimen
not shown:
(close )
|
Genetic Background:
|
Not Specified
|
|
Mutant Allele(s):
|
Shhtm1Chg/Shhtm1Chg
|
|
Age:
|
embryonic day 9.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS15: trunk somite |
Present |
Regionally restricted |
|
Expression is present in the epaxial domain, but it is significantly reduced from wild type. It was in the newly formed somites and those at the interlimb level (in the dorsomedial quadrant); it was virtually absent in the mature, cranial somites.
|
Specimen
not shown:
embryonic day 9.5; Shhtm1Chg/ Shhtm1Chg
(more )
Note: This specimen was stained as a whole mount, embedded in gelatin, and cut on a vibratome.
Specimen
not shown:
(close )
|
Genetic Background:
|
Not Specified
|
|
Mutant Allele(s):
|
Shhtm1Chg/Shhtm1Chg
|
|
Age:
|
embryonic day 9.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section from whole mount
|
|
Embedding:
|
Gelatin
|
|
Note:
|
This specimen was stained as a whole mount, embedded in gelatin, and cut on a vibratome.
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS15: trunk somite |
Present |
Regionally restricted |
|
Expression is present in the epaxial domain, but it is reduced compared to wild type.
|
Specimen
3C:
embryonic day 10.5
(more )
Note: This specimen was stained as a whole mount, embedded in gelatin, and cut on a vibratome.
Specimen
3C:
(close )
|
Genetic Background:
|
Not Specified
|
|
Age:
|
embryonic day 10.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section from whole mount
|
|
Embedding:
|
Gelatin
|
|
Note:
|
This specimen was stained as a whole mount, embedded in gelatin, and cut on a vibratome.
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS17: trunk dermomyotome |
Present |
Regionally restricted |
3C
|
Present in the epaxial and hypaxial domains.
|
Specimen
3D:
embryonic day 10.5; ShhDsh/ ShhDsh
(more )
Note: The somites of mutant embryos display significant malformations. In the dorsomedial region next to the neural tube, no epithelium was discernible. This specimen was embedded in gelatin and cut on a vibratome.
Specimen
3D:
(close )
|
Genetic Background:
|
involves: 101 * C3H
|
|
Mutant Allele(s):
|
ShhDsh/ShhDsh
|
|
Age:
|
embryonic day 10.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section from whole mount
|
|
Embedding:
|
Gelatin
|
|
Note:
|
The somites of mutant embryos display significant malformations. In the dorsomedial region next to the neural tube, no epithelium was discernible. This specimen was embedded in gelatin and cut on a vibratome.
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS17: trunk dermomyotome |
Present |
Regionally restricted |
3D
|
Expression is present in the hypaxial domain and absent from the epaxial domain.
|
Specimen
not shown:
embryonic day 10.5; Shhtm1Chg/ Shhtm1Chg
(more )
Note: The somites of mutant embryos display significant malformations. In the dorsomedial region next to the neural tube, no epithelium was discernible. This specimen was embedded in gelatin and cut on a vibratome.
Specimen
not shown:
(close )
|
Genetic Background:
|
Not Specified
|
|
Mutant Allele(s):
|
Shhtm1Chg/Shhtm1Chg
|
|
Age:
|
embryonic day 10.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section from whole mount
|
|
Embedding:
|
Gelatin
|
|
Note:
|
The somites of mutant embryos display significant malformations. In the dorsomedial region next to the neural tube, no epithelium was discernible. This specimen was embedded in gelatin and cut on a vibratome.
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS17: trunk dermomyotome |
Present |
Regionally restricted |
|
Expression is present in the hypaxial domain and absent from the epaxial domain.
|
Specimen
3E:
embryonic day 10.5; ShhDsh/ ShhDsh
(more )
Note: The somites of mutant embryos display significant malformations. In the dorsomedial region next to the neural tube, no epithelium was discernible. This specimen was embedded in gelatin and cut on a vibratome.
Specimen
3E:
(close )
|
Genetic Background:
|
involves: 101 * C3H
|
|
Mutant Allele(s):
|
ShhDsh/ShhDsh
|
|
Age:
|
embryonic day 10.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section from whole mount
|
|
Embedding:
|
Gelatin
|
|
Note:
|
The somites of mutant embryos display significant malformations. In the dorsomedial region next to the neural tube, no epithelium was discernible. This specimen was embedded in gelatin and cut on a vibratome.
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS17: trunk dermomyotome |
Present |
Regionally restricted |
3E
|
Present in the hypaxial domain.
|
| TS17: trunk sclerotome |
Present |
Regionally restricted |
3E
|
Expression is present in the caudal part of the embryo, towards the notochord.
|
Specimen
not shown:
embryonic day 10.5; Shhtm1Chg/ Shhtm1Chg
(more )
Note: The somites of mutant embryos display significant malformations. In the dorsomedial region next to the neural tube, no epithelium was discernible. This specimen was embedded in gelatin and cut on a vibratome.
Specimen
not shown:
(close )
|
Genetic Background:
|
Not Specified
|
|
Mutant Allele(s):
|
Shhtm1Chg/Shhtm1Chg
|
|
Age:
|
embryonic day 10.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section from whole mount
|
|
Embedding:
|
Gelatin
|
|
Note:
|
The somites of mutant embryos display significant malformations. In the dorsomedial region next to the neural tube, no epithelium was discernible. This specimen was embedded in gelatin and cut on a vibratome.
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS17: trunk dermomyotome |
Present |
Regionally restricted |
|
Present in the hypaxial domain.
|
| TS17: trunk sclerotome |
Present |
Regionally restricted |
|
Expression is present in the caudal part of the embryo, towards the notochord.
|
|
Analysis Tools