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Gene Expression Data
Assay Details
Assay
Reference: J:70745 Suda Y, et al., Emx2 directs the development of diencephalon in cooperation with Otx2. Development. 2001 Jul;128(13):2433-50
Assay type: RNA in situ
MGI Accession ID: MGI:2148272
Gene symbol: Tcf7l2
Gene name: transcription factor 7 like 2, T cell specific, HMG box
Probe: mTcf-4 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 2A: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: diencephalon Strong Regionally restricted 2A Strong expression in dorsal thalamus and pretectum; weak expression in ventral thalamus.
Specimen 2B: embryonic day 11.5; Emx2tm1Sia/Emx2tm1Sia, Otx2tm1Sia/Otx2+ (more )
Note: Emx2 and Otx2 heterozygotes were maintained by crosses with CBA mice. Single Emx2 and Otx2 heterozygotes (from F3 and F5 generations, respectively) were mated to generate double heterozygotes, which were subsequently mated to generate the double mutants.
Structure Level Pattern Image Note
TS19: diencephalon Present Regionally restricted 2B Traces of structures displaying intense expression, including posterior commissure (probably corresponds to posterior pretectum).
TS19: midbrain Present Regionally restricted 2B Traces of structures displaying intense expression, including posterior commissure (probably corresponds to posterior pretectum).
Specimen 7I: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: diencephalon Present 7I
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory