Gene Expression Data
Assay Details
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Assay
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Reference:
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J:69855
Martinez-Morales JR, et al., Otx genes are required for tissue specification in the developing eye. Development. 2001 Jun;128(11):2019-30
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:2137646
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Gene symbol:
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Cryaa
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Gene name:
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crystallin, alpha A
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Results
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Specimen
7A:
embryonic day 10.5
(more  )
Specimen
7A:
(close  )
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Genetic Background:
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involves: DBA/2 * C57BL/6
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Specimen
7B:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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Mutant Allele(s):
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Otx1tm1Asim/Otx1+
Otx2tm1Pas/Otx2+
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: lens pit |
Weak |
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7B
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The lens vesicle is poorly invaginated.
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Specimen
7C:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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Mutant Allele(s):
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Otx1tm1Asim/Otx1tm1Asim
Otx2tm1Pas/Otx2+
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: lens pit |
Absent |
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7C
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The lens vesicle has failed to invaginate in this mutant.
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Specimen
7D:
embryonic day 12.5
(more )
Specimen
7D:
(close )
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Genetic Background:
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involves: DBA/2 * C57BL/6
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Specimen
7E:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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Mutant Allele(s):
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Otx1tm1Asim/Otx1+
Otx2tm1Pas/Otx2+
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: lens vesicle |
Present |
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7E
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The lens is malformed in mutant embryos.
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Specimen
7F:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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Mutant Allele(s):
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Otx1tm1Asim/Otx1tm1Asim
Otx2tm1Pas/Otx2+
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: lens vesicle |
Present |
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7F
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The lens is malformed in this mutant.
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Analysis Tools