Summary | Mutation origin | Mutation description | Expression | Find Mice (IMSR) | Notes | References

Symbol:	Vegfatm1Nagy
Name:	vascular endothelial growth factor A; targeted mutation 1, Andras Nagy
MGI ID:	MGI:1889785
Synonyms:	VEGF-LACZ-KI
Gene:	Vegfa  Location: Chr17:46327919-46343295 bp, - strand  Genetic Position: Chr17, 22.79 cM
Alliance:	Vegfatm1Nagy page

Germline Transmission:	Earliest citation of germline transmission: J:56939
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Reporter) Mutation:    Insertion   Mutation details: The allele expresses a bicistronic mRNA. An IRES-LacZ gene was inserted into exon 8 of the Vegf 3'UTR. This allele contains the selectable PGK-neo marker between two LoxP sites. (J:56939)

In Mice Carrying this Mutation:

5 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Vegfa Mutation:	37 strains or lines available

Original:	J:56939 Miquerol L, et al., Multiple developmental roles of VEGF suggested by a LacZ-tagged allele. Dev Biol. 1999 Aug 15;212(2):307-22
All:	10 reference(s)