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Gene Expression Data
Assay Details
Assay
Reference: J:62022 Leitges M, et al., The paired homeobox gene Uncx4.1 specifies pedicles, transverse processes and proximal ribs of the vertebral column. Development. 2000 Jun;127(11):2259-67
Assay type: RNA in situ
MGI Accession ID: MGI:1859385
Gene symbol: Scx
Gene name: scleraxis scleraxis bHLH transcription factor
Probe: Scx cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 8. A. WT: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: axial skeleton Present Regionally restricted 8A wild type Expression is detected in the mesenchymal anlagen of the pedicles and ribs.
TS19: rib pre-cartilage condensation Present Regionally restricted 8A wild type Expression is detected in the mesenchymal anlagen of the pedicles and ribs.
Specimen 8. A. -/-: embryonic day 11.5; Uncxtm1Akis/Uncxtm1Akis (more )
Structure Level Pattern Image Note
TS19: axial skeleton Present Regionally restricted 8A mutant Reduced expression in the mesenchymal anlagen of the pedicles and ribs compared to wild-type.
TS19: rib pre-cartilage condensation Present Regionally restricted 8A mutant Reduced expression in the mesenchymal anlagen of the pedicles and ribs compared to wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory