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Pitx2 cDNA Probe Detail
Nucleotide
Probe/Clone
  • Name
    Pitx2 cDNA
  • Sequence Type
    cDNA
  • ID
    MGI:1351202
  • Region Covered
    nucleotide 14-1759
  • Vector Type
    Plasmid
  • Note
    The probe recognized all three Pitx2 isoforms.
Source
  • Species
    Not Specified
Genes
Pitx2 paired-like homeodomain transcription factor 2
Expression
  • Assay Results
    97
References
J:49337 Ryan AK, et al., Pitx2 determines left-right asymmetry of internal organs in vertebrates. Nature. 1998 Aug 6;394(6693):545-51
J:54575 Marszalek JR, et al., Situs inversus and embryonic ciliary morphogenesis defects in mouse mutants lacking the KIF3A subunit of kinesin-II. Proc Natl Acad Sci U S A. 1999 Apr 27;96(9):5043-8
J:57950 Tsukui T, et al., Multiple left-right asymmetry defects in Shh(-/-) mutant mice unveil a convergence of the shh and retinoic acid pathways in the control of Lefty-1. Proc Natl Acad Sci U S A. 1999 Sep 28;96(20):11376-81
J:56972 Constam DB, et al., Tissue-specific requirements for the proprotein convertase furin/SPC1 during embryonic turning and heart looping. Development. 2000 Jan;127(2):245-54
J:77125 Norris DP, et al., The Foxh1-dependent autoregulatory enhancer controls the level of Nodal signals in the mouse embryo. Development. 2002 Jul;129(14):3455-68
J:92872 Bamforth SD, et al., Cited2 controls left-right patterning and heart development through a Nodal-Pitx2c pathway. Nat Genet. 2004 Dec;36(11):1189-96
J:94418 Vincent SD, et al., Asymmetric Nodal expression in the mouse is governed by the combinatorial activities of two distinct regulatory elements. Mech Dev. 2004 Nov;121(11):1403-15
J:268103 Dykes IM, et al., A Requirement for Zic2 in the Regulation of Nodal Expression Underlies the Establishment of Left-Sided Identity. Sci Rep. 2018 Jul 11;8(1):10439
J:278736 Cheong A, et al., A null allele of Dnaaf2 displays embryonic lethality and mimics human ciliary dyskinesia. Hum Mol Genet. 2019 Aug 15;28(16):2775-2784

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory