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Gene Expression Data
Assay Details
Assay
Reference: J:53473 Niederreither K, et al., Retinoic acid synthesis and hindbrain patterning in the mouse embryo. Development. 2000 Jan;127(1):75-85
Assay type: Immunohistochemistry
MGI Accession ID: MGI:1350665
Gene symbol: Nefm
Gene name: neurofilament, medium polypeptide
Antibody: anti-neurofilament clone 2H3
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 7A WT: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: facio-acoustic preganglion complex Present Regionally restricted 7A Expression is in nerves.
TS15: future midbrain Present Regionally restricted 7A Expression is in nerves.
TS15: future hindbrain Present Single cells 7A There is expression in a few nerve fibers.
Specimen 7B -/-: embryonic day 9.5; Aldh1a2tm1Ipc/Aldh1a2tm1Ipc (more )
Structure Level Pattern Image Note
TS15: future midbrain Present Regionally restricted 7B Expression is in nerves.
TS15: facio-acoustic preganglion complex Strong Uniform 7B Fasiculation does not take place normally.
TS15: future hindbrain Absent 7B
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
MGI 6.23 		The Jackson Laboratory