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Gene Expression Data
Assay Details
Assay
Reference: J:41551 Dupe V, et al., Key roles of retinoic acid receptors alpha and beta in the patterning of the caudal hindbrain, pharyngeal arches and otocyst in the mouse. Development. 1999 Nov;126(22):5051-9
Assay type: RNA in situ
MGI Accession ID: MGI:1346588
Gene symbol: Crabp1
Gene name: cellular retinoic acid binding protein I
Probe: Crabp-1 cDNA1
Probe preparation: Antisense RNA
Results
Specimen 4A left: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: 2nd branchial arch Present Regionally restricted 4a left Expression is present in two broad subectodermal sheets of neural crest cells arising from rhombomeres 4, 6 & 7; they colonize the periphery of the 2nd, 3rd & 4th arches, respectively, enveloping negative mesenchymal cells derived from paraxial mesoderm.
TS15: 3rd branchial arch Present Regionally restricted 4a left Expression is present in two broad subectodermal sheets of neural crest cells arising from rhombomeres 4, 6 & 7; they colonize the periphery of the 2nd, 3rd & 4th arches, respectively, enveloping negative mesenchymal cells derived from paraxial mesoderm.
TS15: branchial arch Present Regionally restricted 4a left Expression is present in two broad subectodermal sheets of neural crest cells arising from rhombomeres 4, 6 & 7; they colonize the periphery of the 2nd, 3rd & 4th arches, respectively, enveloping negative mesenchymal cells derived from paraxial mesoderm.
TS15: migrating neural crest Present Regionally restricted 4a left Expression is present in two broad subectodermal sheets of neural crest cells arising from rhombomeres 4, 6 & 7; they colonize the periphery of the 2nd, 3rd & 4th arches, respectively, enveloping negative mesenchymal cells derived from paraxial mesoderm.
TS15: rhombomere 4 Strong 4a left
TS15: rhombomere 6 Strong 4a left
TS15: neural tube Present Graded 4a left Expression gradually decreases in r7 and more posterior regions of the neural tube.
TS15: rhombomere 7 Present Graded 4a left Expression gradually decreases in r7 and more posterior regions of the neural tube.

Specimen 4A right: embryonic day 9.5; Raratm1Ipc/Raratm1Ipc, Rarbtm1Ipc/Rarbtm1Ipc (more )
Structure Level Pattern Image Note
TS15: 2nd branchial arch Present Single cells 4a right Expression in this mutant is the same as in wild-type embryos. No significant alterations in the number and migratory paths of neural crest cells in the pharyngeal arches were detected.
TS15: 3rd branchial arch Present Single cells 4a right Expression in this mutant is the same as in wild-type embryos. No significant alterations in the number and migratory paths of neural crest cells in the pharyngeal arches were detected.
TS15: branchial arch Present Single cells 4a right Expression in this mutant is the same as in wild-type embryos. No significant alterations in the number and migratory paths of neural crest cells in the pharyngeal arches were detected.
TS15: migrating neural crest Present Single cells 4a right Expression in this mutant is the same as in wild-type embryos. No significant alterations in the number and migratory paths of neural crest cells in the pharyngeal arches were detected.
TS15: neural tube Strong 4a right In mutants, the domain of stronger expression had expanded caudally, reaching the level of the first spinal ganglion.
TS15: rhombomere 4 Strong 4a right In mutants, the domain of stronger expression had expanded caudally, reaching the level of the first spinal ganglion.
TS15: rhombomere 6 Strong 4a right In mutants, the domain of stronger expression had expanded caudally, reaching the level of the first spinal ganglion.
TS15: rhombomere 7 Strong 4a right In mutants, the domain of stronger expression had expanded caudally, reaching the level of the first spinal ganglion.
TS15: spinal ganglion Strong 4a right In mutants, the domain of stronger expression had expanded caudally, reaching the level of the first spinal ganglion.

Specimen 4B left: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: 2nd branchial arch Present Single cells 4b left Expression is present in two broad subectodermal sheets of neural crest cells arising from rhombomeres 4, 6 & 7; they colonize the periphery of the 2nd, 3rd & 4th arches, respectively, enveloping negative mesenchymal cells derived from paraxial mesoderm.
TS15: 3rd branchial arch Present Single cells 4b left Expression is present in two broad subectodermal sheets of neural crest cells arising from rhombomeres 4, 6 & 7; they colonize the periphery of the 2nd, 3rd & 4th arches, respectively, enveloping negative mesenchymal cells derived from paraxial mesoderm.
TS15: branchial arch Present Single cells 4b left Expression is present in two broad subectodermal sheets of neural crest cells arising from rhombomeres 4, 6 & 7; they colonize the periphery of the 2nd, 3rd & 4th arches, respectively, enveloping negative mesenchymal cells derived from paraxial mesoderm.

Specimen 4B right: embryonic day 9.5; Raratm1Ipc/Raratm1Ipc, Rarbtm1Ipc/Rarbtm1Ipc (more )
Structure Level Pattern Image Note
TS15: 2nd branchial arch Present Single cells 4b right Expression in this mutant is the same as in wild-type embryos. No significant alterations in the number and migratory paths of neural crest cells in the pharyngeal arches were detected.
TS15: 3rd branchial arch Present Single cells 4b right Expression in this mutant is the same as in wild-type embryos. No significant alterations in the number and migratory paths of neural crest cells in the pharyngeal arches were detected.
TS15: branchial arch Present Single cells 4b right Expression in this mutant is the same as in wild-type embryos. No significant alterations in the number and migratory paths of neural crest cells in the pharyngeal arches were detected.

Specimen A[a] mutant: embryonic day 9.5; Raratm1Ipc/Raratm1Ipc (more )
Structure Level Pattern Image Note
TS15: 2nd branchial arch Present Single cells Expression in this mutant is the same as in wild-type embryos.
TS15: 3rd branchial arch Present Single cells Expression in this mutant is the same as in wild-type embryos.
TS15: branchial arch Present Single cells Expression in this mutant is the same as in wild-type embryos.
TS15: neural tube Present Expression in this mutant is the same as in wild-type embryos.
TS15: rhombomere 4 Present Expression in this mutant is the same as in wild-type embryos.
TS15: rhombomere 6 Present Expression in this mutant is the same as in wild-type embryos.
TS15: rhombomere 7 Present Expression in this mutant is the same as in wild-type embryos.

Specimen A[b] mutant: embryonic day 9.5; Rarbtm1Mma/Rarbtm1Mma (more )
Structure Level Pattern Image Note
TS15: 2nd branchial arch Present Single cells Expression in this mutant is the same as in wild-type embryos.
TS15: 3rd branchial arch Present Single cells Expression in this mutant is the same as in wild-type embryos.
TS15: branchial arch Present Single cells Expression in this mutant is the same as in wild-type embryos.
TS15: neural tube Present Expression in this mutant is the same as in wild-type embryos.
TS15: rhombomere 4 Present Expression in this mutant is the same as in wild-type embryos.
TS15: rhombomere 6 Present Expression in this mutant is the same as in wild-type embryos.
TS15: rhombomere 7 Present Expression in this mutant is the same as in wild-type embryos.


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory