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Gene Expression Data
Assay Details
Assay
Reference: J:54640 Pearce JJ, et al., A mouse cerberus/Dan-related gene family. Dev Biol. 1999 May 1;209(1):98-110
Assay type: RNA in situ
MGI Accession ID: MGI:1345394
Gene symbol: Grem1
Gene name: gremlin 1, DAN family BMP antagonist
Probe: Drm probe1
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 6A: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: trunk unsegmented mesenchyme Present Regionally restricted 6A Expression was confined to a stripe of mesoderm at the lateral edge of the presomitic mesoderm.
TS13: head somite Present Regionally restricted 6A More anteriorly, expression was found in the lateral-most aspects of the developing somites.
TS13: trunk somite Present Regionally restricted 6A More anteriorly, expression was found in the lateral-most aspects of the developing somites.

Specimen 6B: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: future prosencephalon Present Regionally restricted 6B Expression was seen in the anterior ventral forebrain.

Specimen 6C: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: trunk somite Present Regionally restricted 6C Expression was seen in the lateral-most aspects of developing somites.
TS15: trunk dermomyotome Present Regionally restricted 6C An additional domain of expression was seen in the medial aspects of the dermamyotome of maturing anterior somites.
TS15: neural tube roof plate Present 6C
TS15: forelimb bud mesenchyme Present Regionally restricted 6C Expression was observed in the dorsal and ventral mesenchyme of the emergent limb buds.

Specimen 6D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: trunk dermomyotome Present Regionally restricted 6D Expression was restricted to the medial and lateral extremes of the dermamyotome, with prominent expression seen in the epithelial balls of the lateral myotome and overlying dermis of the interlimb region.
TS17: limb Present Regionally restricted 6D Expression becomes restricted to a dorsal proximal domain.

Specimen 6E: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: diencephalon roof plate Present 6E

Specimen 6F: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: trunk unsegmented mesenchyme Present Regionally restricted 6F Expression was confined to a stripe of mesoderm at the lateral edge of the presomitic mesoderm.

Specimen 6G: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: trunk somite Present Regionally restricted 6G Expression was seen in the lateral-most aspects of developing somites.
TS15: trunk dermomyotome Present Regionally restricted 6G An additional domain of expression was seen in the medial aspects of the dermamyotome of maturing anterior somites.
TS15: forelimb bud mesenchyme Present Regionally restricted 6G Expression was observed in the dorsal and ventral mesenchyme of the emergent limb buds.

Specimen 6H: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future hindbrain Present Regionally restricted 6H Expression was restricted to the roof plate at the midbrain-hindbrain junction area.
TS15: future midbrain roof plate Present Regionally restricted 6H Expression was restricted to the roof plate at the midbrain-hindbrain junction area.

Specimen not shown: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: neural tube Absent

Specimen 6I: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: outer ear Present 6I

Specimen 6J: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: limb Present Regionally restricted 6J Expression becomes restricted to the proximal interdigital regions.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory