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Gene Expression Data
Assay Details
Assay
Reference: J:40215 Wehrle-Haller B, et al., Soluble and cell-bound forms of steel factor activity play distinct roles in melanocyte precursor dispersal and survival on the lateral neural crest migration pathway. Development. 1995 Mar;121(3):731-42
Assay type: RNA in situ
MGI Accession ID: MGI:1341017
Gene symbol: Kit
Gene name: KIT proto-oncogene receptor tyrosine kinase
Probe: c-kit probe
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen not shown: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: embryo Present Expression was observed in the head and trunk.

Specimen 1.A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: 1st branchial groove Present 1A
TS17: 2nd branchial groove Present 1A
TS17: 3rd branchial groove Present 1A
TS17: 4th branchial groove Present 1A
TS17: otocyst Present 1A
TS17: embryo Present Regionally restricted 1A Expression is detected in putative migrating cranial crest cells (located between the forebrain-midbrain junction and the eye, at the level of the midbrain-hindbrain junction, and posterior to the otic vesicle).

Specimen 1.C: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: head mesenchyme Present Graded 1C Expressing cells were present in the head mesenchyme, particularly in the region between the eye, forebrain, and nose.
TS18: branchial arch Present Regionally restricted 1C Expression was detected in the posterior regions of the branchial arch.
TS18: 2nd branchial arch Present Regionally restricted 1C Expression was detected in the posterior regions of the hyoid arch.
TS18: trunk mesenchyme Present Regionally restricted 1C Expressing cells were observed from the first somites to the level of the hindlimb buds in the same locations as cells expressing Dct (TRP-2) mRNA.

Specimen 1.E: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: head mesenchyme Present Regionally restricted 1E Expressing cells were localized in a stripe originating at the mid-to-hindbrain junction and extending towards the eye.
TS18: trunk mesenchyme Present Regionally restricted 1E Positive cells were detected in the lateral mesenchyme.
TS18: neural tube Present Regionally restricted 1E Positive cells were detected in the dorsal neural tube.
TS18: forelimb bud Present 1E
TS18: hindgut Present 1E
TS18: hindlimb bud Present 1E

Specimen 2.C: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: trunk somite Present Spotted 2C Expression was dispersed over the somite surface.
TS19: trunk mesenchyme Present Spotted 2C Expression was detected in the lateral mesenchyme.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory