About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:30343 Torres M, et al., Pax-2 controls multiple steps of urogenital development. Development. 1995 Dec;121(12):4057-65
Assay type: RNA in situ
MGI Accession ID: MGI:1335313
Gene symbol: Ret
Gene name: ret proto-oncogene
Probe: Ret cDNA5
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 3A c-ret +/+: embryonic day 9.5 (more )
Note: This embryo was embedded in gelatin and vibratome sectioned.
Structure Level Pattern Image Note
TS15: nephric duct Present 3A Authors state expression is detected in the Wolffian duct.
TS15: genitourinary system Present Regionally restricted 3A Authors state expression is in the ureter.

Specimen 3B c-ret -/-: embryonic day 9.5; Pax2tm1Pgr/Pax2tm1Pgr (more )
Note: This embryo was embedded in gelatin and vibratome sectioned.
Structure Level Pattern Image Note
TS15: nephric duct Present 3B Expression in this mutant is the same as in wild-type embryos.
TS15: genitourinary system Present Regionally restricted 3B Expression in this mutant is the same as in wild-type embryos. Expession is in the ureter.

Specimen 3C c-ret -/-: embryonic day 10.5; Pax2tm1Pgr/Pax2tm1Pgr (more )
Note: This embryo was embedded in gelatin and vibratome sectioned.
Structure Level Pattern Image Note
TS17: nephric duct Absent 3C

Specimen 3D c-ret +/+: embryonic day 10.5 (more )
Note: This embryo was embedded in gelatin and vibratome sectioned.
Structure Level Pattern Image Note
TS17: nephric duct Present 3D

Specimen 3E +/+ embryo: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: nephric duct Present 3E +/+

Specimen 3E -/- embryos: embryonic day 11.5; Pax2tm1Pgr/Pax2tm1Pgr (more )
Structure Level Pattern Image Note
TS19: nephric duct Absent 3E -/- In mutant embryos, the nephric (Wolffian) duct does not extend past somite 25.

Specimen 10A c-ret +/+: embryonic day 11.5 (more )
Note: This embryo was embedded in gelatin and vibratome sectioned.
Structure Level Pattern Image Note
TS19: nephric duct Present 10A This is in the Wolffian duct where the ureter buds out.
TS19: ureteric bud Present 10A This is in the Wolffian duct where the ureter buds out.

Specimen 10B c-ret -/-: embryonic day 11.5; Pax2tm1Pgr/Pax2tm1Pgr (more )
Note: This embryo was embedded in gelatin and vibratome sectioned.
Structure Level Pattern Image Note
TS19: nephric duct Absent 10B This is in the Wolffian duct where the ureter buds out.
TS19: ureteric bud Absent 10B This is in the Wolffian duct where the ureter buds out.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
05/07/2024
MGI 6.23
The Jackson Laboratory