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Gene Expression Data
Assay Details
Assay
Reference: J:53293 Chang H, et al., Smad5 knockout mice die at mid-gestation due to multiple embryonic and extraembryonic defects. Development. 1999 Apr;126(8):1631-42
Assay type: RNA in situ
MGI Accession ID: MGI:1334630
Gene symbol: Foxa2
Gene name: forkhead box A2
Probe: HNF3-beta-cDNA1
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 5A: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS10: extraembryonic visceral endoderm Present 5A
TS10: node Present 5A
TS10: embryo endoderm Present Regionally restricted 5A Expression is detected in the anterior migrating mesoderm and endoderm cells of the head process.
TS10: embryo mesoderm Present Regionally restricted 5A Expression is detected in the anterior migrating mesoderm and endoderm cells of the head process.

Specimen 5B: embryonic day 7.5; Smad5tm1Zuk/Smad5tm1Zuk (more )
Structure Level Pattern Image Note
TS11: extraembryonic visceral endoderm Present 5B
TS11: node Present 5B
TS11: embryo endoderm Present Regionally restricted 5B Expression is detected in the anterior migrating mesoderm and endoderm cells of the head process.
TS11: head mesenchyme Present Regionally restricted 5B Expression is detected in the anterior migrating mesoderm and endoderm cells of the head process.

Specimen 5C: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: foregut diverticulum Strong 5C
TS13: hindgut diverticulum Strong 5C
TS13: notochord Strong 5C
TS13: future brain Strong Regionally restricted 5C Expression is detected in several areas of the developing brain and neural tube.
TS13: neural tube Strong Regionally restricted 5C Expression is detected in several areas of the developing brain and neural tube.

Specimen 5D: embryonic day 8.5; Smad5tm1Zuk/Smad5tm1Zuk (more )
Structure Level Pattern Image Note
TS13: foregut diverticulum Strong 5D
TS13: hindgut diverticulum Strong 5D
TS13: notochord Strong 5D
TS13: future brain Strong Regionally restricted 5D Expression is detected in several areas of the developing brain and neural tube.
TS13: neural tube Strong Regionally restricted 5D Expression is detected in several areas of the developing brain and neural tube.

Specimen 5E: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: embryo Present 5E

Specimen 5F: embryonic day 9.5; Smad5tm1Zuk/Smad5tm1Zuk (more )
Structure Level Pattern Image Note
TS15: embryo Present 5F


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory