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Gene Expression Data
Assay Details
Assay
Reference: J:1679 Del Amo FF, et al., Expression pattern of Motch, a mouse homolog of Drosophila Notch, suggests an important role in early postimplantation mouse development. Development. 1992 Jul;115(3):737-44
Assay type: RNA in situ
MGI Accession ID: MGI:1333991
Gene symbol: Notch1
Gene name: notch 1
Probe: Notch1 cDNA5
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 5.A: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: tail unsegmented mesenchyme Very strong 5A
TS15: neural tube Present 5A
TS15: dorsal aorta Present 5A Expression is detected in endothelial cells lining the dorsal aorta.

Specimen 5.B: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future brain Present 5B Expression is noted in the brain and in the meninges.

Specimen 5.C: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: heart Present 5C Expression is detected in the endocardium of the heart.
TS15: branchial arch Present 5C Expression is detected in endothelial cells lining blood vessels in the branchial arches.

Specimen 5.D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: dorsal root ganglion Present 5D
TS17: future spinal cord Present 5D
TS17: mesonephros Present 5D
TS17: cardiovascular system Present Regionally restricted 5D Expression is detected in intersomitic blood vessels.

Specimen 5.E: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: cardiovascular system Present Regionally restricted 5E Expression is detected in endothelial cells lining the intersomitic blood vessels.
TS17: trunk somite Present Regionally restricted 5E Expression is detected in the sclerotome; no expression is seen in the dermatome or myotome.

Specimen 5.F: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: future spinal cord Present Regionally restricted 5F Expression is detected in the mitotic cells of the ventricular zone of the spinal cord. No expression is seen in the floor plate or postmitotic cells of the ventral horn of the spinal cord.
TS17: dorsal root ganglion Present Regionally restricted 5F

Specimen 5.G: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: trigeminal ganglion Present 5G

Specimen 5.H: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS18: latero-nasal process Strong Regionally restricted 5H Strong expression was seen in the surface ectoderm of the lateral nasal process.
TS18: medial-nasal process Moderate Regionally restricted 5H Ectoderm and mesenchyme of the medial nasal process express at lower levels.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory