Tfap2a RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:53294 Solloway MJ, et al., Early embryonic lethality in Bmp5;Bmp7 double mutant mice suggests functional redundancy within the 60A subgroup. Development. 1999 Apr;126(8):1753-68
Assay type:	RNA in situ
MGI Accession ID:	MGI:1333139
Gene symbol:	Tfap2a
Gene name:	transcription factor AP-2, alpha

Probe:	AP-2 probe2
Probe preparation:	Antisense labelled with digoxigenin RNA
Visualized with:	Alkaline phosphatase

Results

7A ©

Specimen 7A: embryonic day 8.5 (more

)

Structure	Level	Pattern	Image	Note
TS13: neural ectoderm	Present	Regionally restricted	7A	Expression is in the dorsal cranial neural folds.

7B ©

Specimen 7B: embryonic day 9.5 (more

)

Structure	Level	Image
TS15: 1st branchial arch mandibular component mesenchyme derived from neural crest	Present	7B
TS15: 2nd branchial arch mesenchyme derived from neural crest	Present	7B
TS15: 3rd branchial arch mesenchyme derived from neural crest	Present	7B
TS15: future midbrain	Present	7B
TS15: head mesenchyme derived from neural crest	Present	7B
TS15: limb	Present	7B
TS15: spinal ganglion	Present	7B

7C ©

Specimen 7C: embryonic day 9.5 (more

)

Structure	Level	Image
TS15: 1st branchial arch mandibular component mesenchyme derived from neural crest	Present	7C
TS15: 2nd branchial arch mesenchyme derived from neural crest	Present	7C
TS15: 3rd branchial arch mesenchyme derived from neural crest	Present	7C
TS15: future midbrain	Present	7C
TS15: head mesenchyme derived from neural crest	Present	7C
TS15: limb	Present	7C
TS15: spinal ganglion	Present	7C

7D ©

Specimen 7D: embryonic day 8.5; Bmp5^se/Bmp5^se, Bmp7^tm1Rob/Bmp7^tm1Rob (more

)

Structure	Level	Pattern	Image	Note
TS13: neural ectoderm	Present	Regionally restricted	7D	Expression is reduced in the rostral neurectoderm of the double-mutant embryos.

7E ©

Specimen 7E: embryonic day 9.5; Bmp5^se/Bmp5^se, Bmp7^tm1Rob/Bmp7^tm1Rob (more

)

Structure	Level	Image	Note
TS15: 1st branchial arch mandibular component mesenchyme derived from neural crest	Present	7E
TS15: 2nd branchial arch mesenchyme derived from neural crest	Present	7E
TS15: 3rd branchial arch mesenchyme derived from neural crest	Present	7E
TS15: future midbrain	Present	7E
TS15: head mesenchyme derived from neural crest	Present	7E
TS15: limb	Present	7E
TS15: spinal ganglion	Weak	7E	Reduced expression in the trunk ganglia.

7F ©

Specimen 7F: embryonic day 9.5; Bmp5^se/Bmp5^se, Bmp7^tm1Rob/Bmp7^tm1Rob (more

)

Structure	Level	Image	Note
TS15: 1st branchial arch mandibular component mesenchyme derived from neural crest	Present	7F
TS15: 2nd branchial arch mesenchyme derived from neural crest	Present	7F
TS15: 3rd branchial arch mesenchyme derived from neural crest	Present	7F
TS15: future midbrain	Present	7F
TS15: head mesenchyme derived from neural crest	Present	7F
TS15: limb	Present	7F
TS15: spinal ganglion	Weak	7F	Reduced expression in the trunk ganglia.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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