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Gene Expression Data
Assay Details
Assay
Reference: J:53294 Solloway MJ, et al., Early embryonic lethality in Bmp5;Bmp7 double mutant mice suggests functional redundancy within the 60A subgroup. Development. 1999 Apr;126(8):1753-68
Assay type: RNA in situ
MGI Accession ID: MGI:1333099
Gene symbol: Wnt1
Gene name: wingless-type MMTV integration site family, member 1
Probe: Wnt1 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 5C left: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future hindbrain Present Regionally restricted 5C left Expression is in the dorsal midbrain and along the midbrain/hindbrain boundary.
TS15: future midbrain Present Regionally restricted 5C left Expression is in the dorsal midbrain and along the midbrain/hindbrain boundary.

Specimen 5C right: embryonic day 9.5; Bmp5se/Bmp5se, Bmp7tm1Rob/Bmp7tm1Rob (more )
Structure Level Pattern Image Note
TS15: future hindbrain Present Regionally restricted 5C right Expression is in the dorsal midbrain and along the midbrain/hindbrain boundary.
TS15: future midbrain Present Regionally restricted 5C right Expression is in the dorsal midbrain and along the midbrain/hindbrain boundary.

Specimen 5G: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: hindbrain Present Regionally restricted 5G Expression is in the dorsal midbrain, the midbrain/hindbrain isthmus, and the edges of the hindbrain roofplate.
TS17: midbrain Present Regionally restricted 5G Expression is in the dorsal midbrain, the midbrain/hindbrain isthmus, and the edges of the hindbrain roofplate.

Specimen 5H: embryonic day 10.5; Bmp5se/Bmp5se, Bmp7tm1Rob/Bmp7tm1Rob (more )
Structure Level Pattern Image Note
TS17: hindbrain Present Regionally restricted 5H Expression is in the dorsal midbrain, the midbrain/hindbrain isthmus, and the edges of the hindbrain roofplate. The hindbrain roofplate is severely reduced in size in double-mutant embryos.
TS17: midbrain Present Regionally restricted 5H Expression is in the dorsal midbrain, the midbrain/hindbrain isthmus, and the edges of the hindbrain roofplate. The hindbrain roofplate is severely reduced in size in double-mutant embryos.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory