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Gene Expression Data
Assay Details
Assay
Reference: J:51598 Casarosa S, et al., Mash1 regulates neurogenesis in the ventral telencephalon. Development. 1999 Feb;126(3):525-34
Assay type: RNA in situ
MGI Accession ID: MGI:1327898
Gene symbol: Gad1
Gene name: glutamate decarboxylase 1
Probe: Gad1 probe-1
Probe preparation: Antisense RNA
Results
Specimen 2C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: telencephalon Strong Regionally restricted 2C Subventricular zone neuronal precursers express high levels of Gad1.

Specimen 2C': embryonic day 12.5; Ascl1tm1And/Ascl1tm1And (more )
Structure Level Pattern Image Note
TS20: ganglionic eminence Present Regionally restricted 2C' Ventricular zone progenitors ectopically express Gad1 at low levels throughout the ganglionic eminences.
TS20: lateral ganglionic eminence Present 2C'
TS20: medial ganglionic eminence Absent 2C'

Specimen 4A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: telencephalon Present Regionally restricted 4A Gad1 is expressed in neurons in the mantle zone and in subventricular zone neuronal precursors. Gad1 is not expressed in ventricular zone progenitors.

Specimen 4A': embryonic day 10.5; Ascl1tm1And/Ascl1tm1And (more )
Structure Level Pattern Image Note
TS17: telencephalon Present Regionally restricted 4A' Gad1 is ectopically expressed in the ventricular zone of the ventral telencephalon.

Specimen 4B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: telencephalon Present Regionally restricted 4B Gad1 is expressed in neurons in the mantle zone and in subventricular zone neuronal precursers. Gad1 is not expressed in ventricular zone progenitors.

Specimen 4B': embryonic day 12.5; Ascl1tm1And/Ascl1tm1And (more )
Structure Level Pattern Image Note
TS20: telencephalon Present Regionally restricted 4B' Gad1 is ectopically expressed in the ventricular zone of the ventral telencephalon.

Specimen 4C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: telencephalon Present Regionally restricted 4C Gad1 is expressed in neurons in the mantle zone and in subventricular zone neuronal precursers. Gad1 is not expressed in ventricular zone progenitors.

Specimen 4C': embryonic day 12.5; Ascl1tm1And/Ascl1tm1And (more )
Structure Level Pattern Image Note
TS20: telencephalon Present Regionally restricted 4C' Gad1 is ectopically expressed in the ventricular zone of the ventral telencephalon.

Specimen 4D: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cerebral cortex subventricular zone Present 4D
TS23: telencephalon mantle layer Present 4D
TS23: telencephalon ventricular layer Absent 4D

Specimen 4D': embryonic day 15.5; Ascl1tm1And/Ascl1tm1And (more )
Structure Level Pattern Image Note
TS23: lateral ganglionic eminence Present Regionally restricted 4D' Expression is detected in the ventricular zone of the lateral ganglionic eminence.

Specimen 6A: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: cerebral cortex intermediate zone Present Regionally restricted 6A
TS25: cerebral cortex marginal zone Present Regionally restricted 6A

Specimen 6A': embryonic day 17.5; Ascl1tm1And/Ascl1tm1And (more )
Structure Level Pattern Image Note
TS25: cerebral cortex intermediate zone Weak Regionally restricted 6A' Expression is reduced in the intermediate zone of the cerebral cortex as compared to wild-type.
TS25: cerebral cortex marginal zone Trace 6A' Expression is almost completely absent in the marginal zone of the cerebral cortex as compared to wild-type.

Specimen 6C: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: olfactory lobe Present 6C

Specimen 6c': embryonic day 18.5; Ascl1tm1And/Ascl1tm1And (more )
Structure Level Pattern Image Note
TS26: olfactory lobe Weak 6C'


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory