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Lefty-2 cDNA1 Probe Detail
Nucleotide
Probe/Clone
  • Name
    Lefty-2 cDNA1
  • Sequence Type
    cDNA
  • ID
    MGI:1278391
  • Region Covered
    3' untranslated (nucleotides 1163-1695)
  • Vector Type
    Plasmid
  • Insert Site
    BglII/EcoRI
  • Insert Size
    0.5kb
Source
  • Species
    mouse, laboratory
Genes
Lefty2 left-right determination factor 2
Expression
  • Assay Results
    54
References
J:49270 Meno C, et al., Two closely-related left-right asymmetrically expressed genes, lefty-1 and lefty-2: their distinct expression domains, chromosomal linkage and direct neuralizing activity in Xenopus embryos. Genes Cells. 1997 Aug;2(8):513-24
J:56972 Constam DB, et al., Tissue-specific requirements for the proprotein convertase furin/SPC1 during embryonic turning and heart looping. Development. 2000 Jan;127(2):245-54
J:67152 Perea-Gomez A, et al., Otx2 is required for visceral endoderm movement and for the restriction of posterior signals in the epiblast of the mouse embryo. Development. 2001 Mar;128(5):753-65
J:80018 Przemeck GK, et al., Node and midline defects are associated with left-right development in Delta1 mutant embryos. Development. 2003 Jan;130(1):3-13
J:186556 Trask MC, et al., Yin-Yang1 is required for epithelial-to-mesenchymal transition and regulation of Nodal signaling during mammalian gastrulation. Dev Biol. 2012 Aug 15;368(2):273-82
J:243754 Khoueiry R, et al., Lineage-specific functions of TET1 in the postimplantation mouse embryo. Nat Genet. 2017 Jul;49(7):1061-1072
J:253966 Sigg MA, et al., Evolutionary Proteomics Uncovers Ancient Associations of Cilia with Signaling Pathways. Dev Cell. 2017 Dec 18;43(6):744-762.e11
J:268103 Dykes IM, et al., A Requirement for Zic2 in the Regulation of Nodal Expression Underlies the Establishment of Left-Sided Identity. Sci Rep. 2018 Jul 11;8(1):10439

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory