Lefty-2 cDNA1
Probe Detail
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Species
mouse, laboratory
Lefty2
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left-right determination factor 2
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J:49270
Meno C, et al., Two closely-related left-right asymmetrically expressed genes, lefty-1 and lefty-2: their distinct expression domains, chromosomal linkage and direct neuralizing activity in Xenopus embryos. Genes Cells. 1997 Aug;2(8):513-24
J:51419
Nonaka S, et al., Randomization of left-right asymmetry due to loss of nodal cilia generating leftward flow of extraembryonic fluid in mice lacking KIF3B motor protein. Cell. 1998 Dec 11;95(6):829-37
J:56972
Constam DB, et al., Tissue-specific requirements for the proprotein convertase furin/SPC1 during embryonic turning and heart looping. Development. 2000 Jan;127(2):245-54
J:67152
Perea-Gomez A, et al., Otx2 is required for visceral endoderm movement and for the restriction of posterior signals in the epiblast of the mouse embryo. Development. 2001 Mar;128(5):753-65
J:80018
Przemeck GK, et al., Node and midline defects are associated with left-right development in Delta1 mutant embryos. Development. 2003 Jan;130(1):3-13
J:186556
Trask MC, et al., Yin-Yang1 is required for epithelial-to-mesenchymal transition and regulation of Nodal signaling during mammalian gastrulation. Dev Biol. 2012 Aug 15;368(2):273-82
J:243754
Khoueiry R, et al., Lineage-specific functions of TET1 in the postimplantation mouse embryo. Nat Genet. 2017 Jul;49(7):1061-1072
J:253966
Sigg MA, et al., Evolutionary Proteomics Uncovers Ancient Associations of Cilia with Signaling Pathways. Dev Cell. 2017 Dec 18;43(6):744-762.e11
J:268103
Dykes IM, et al., A Requirement for Zic2 in the Regulation of Nodal Expression Underlies the Establishment of Left-Sided Identity. Sci Rep. 2018 Jul 11;8(1):10439