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pGli-2 Probe Detail
Nucleotide
Probe/Clone
  • Name
    pGli-2
  • Sequence Type
    cDNA
  • ID
    MGI:12279
  • Region Covered
    contains sequences from 480bp 5' to the zinc finger domain to the middle of fourth zinc finger
  • Vector Type
    Plasmid
Source
  • Species
    mouse, laboratory
Genes
Gli2 GLI-Kruppel family member GLI2
Expression
  • Assay Results
    198
References
J:4086 Hui CC, et al., A mouse model of greig cephalopolysyndactyly syndrome: the extra-toesJ mutation contains an intragenic deletion of the Gli3 gene. Nat Genet. 1993 Mar;3(3):241-6
J:17485 Hui CC, et al., Expression of three mouse homologs of the Drosophila segment polarity gene cubitus interruptus, Gli, Gli-2, and Gli-3, in ectoderm- and mesoderm-derived tissues suggests multiple roles during postimplantation development. Dev Biol. 1994 Apr;162(2):402-13
J:38381 Mo R, et al., Specific and redundant functions of Gli2 and Gli3 zinc finger genes in skeletal patterning and development. Development. 1997 Jan;124(1):113-23
J:40390 Sasaki H, et al., A binding site for Gli proteins is essential for HNF-3beta floor plate enhancer activity in transgenics and can respond to Shh in vitro. Development. 1997 Apr;124(7):1313-22
J:40587 Persengiev SP, et al., Gli family members are differentially expressed during the mitotic phase of spermatogenesis. Oncogene. 1997 May 15;14(19):2259-64
J:41684 Lee J, et al., Gli1 is a target of Sonic hedgehog that induces ventral neural tube development. Development. 1997 Jul;124(13):2537-52
J:42454 Grindley JC, et al., Evidence for the involvement of the Gli gene family in embryonic mouse lung development. Dev Biol. 1997 Aug 15;188(2):337-48
J:45211 Buscher D, et al., Expression profile of Gli family members and Shh in normal and mutant mouse limb development. Dev Dyn. 1998 Jan;211(1):88-96
J:49164 Ding Q, et al., Diminished Sonic hedgehog signaling and lack of floor plate differentiation in Gli2 mutant mice. Development. 1998 Jul;125(14):2533-43
J:59288 Baur ST, et al., Combinatorial signaling through BMP receptor IB and GDF5: shaping of the distal mouse limb and the genetics of distal limb diversity. Development. 2000 Feb;127(3):605-19
J:60986 Park HL, et al., Mouse Gli1 mutants are viable but have defects in SHH signaling in combination with a Gli2 mutation. Development. 2000 Apr;127(8):1593-605
J:64180 Outram SV, et al., Hedgehog signaling regulates differentiation from double-negative to double-positive thymocyte. Immunity. 2000 Aug;13(2):187-97
J:72303 Haraguchi R, et al., Unique functions of Sonic hedgehog signaling during external genitalia development. Development. 2001 Nov;128(21):4241-50
J:73074 Bai CB, et al., Gli1 can rescue the in vivo function of Gli2. Development. 2001 Dec;128(24):5161-72
J:73075 Dahmane N, et al., The Sonic Hedgehog-Gli pathway regulates dorsal brain growth and tumorigenesis. Development. 2001 Dec;128(24):5201-12
J:104154 Rice R, et al., Expression patterns of Hedgehog signalling pathway members during mouse palate development. Gene Expr Patterns. 2006 Jan;6(2):206-12
J:119875 Lebel M, et al., Gli2 and Gli3 play distinct roles in the dorsoventral patterning of the mouse hindbrain. Dev Biol. 2007 Feb 1;302(1):345-55
J:153731 Pazin DE, et al., Developmental expression of Smoc1 and Smoc2 suggests potential roles in fetal gonad and reproductive tract differentiation. Dev Dyn. 2009 Nov;238(11):2877-90
J:158583 Ko HW, et al., Broad-minded links cell cycle-related kinase to cilia assembly and hedgehog signal transduction. Dev Cell. 2010 Feb 16;18(2):237-47
J:170258 Mavromatakis YE, et al., Foxa1 and Foxa2 positively and negatively regulate Shh signalling to specify ventral midbrain progenitor identity. Mech Dev. 2011 Jan-Feb;128(1-2):90-103
J:306168 Haraguchi R, et al., New Insights into Development of Female Reproductive Tract-Hedgehog-Signal Response in Wolffian Tissues Directly Contributes to Uterus Development. Int J Mol Sci. 2021 Jan 26;22(3)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory