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tip Gene Detail
Summary
  • Symbol
    tip
  • Name
    tippy
  • Feature Type
    heritable phenotypic marker
  • IDs
    MGI:98757
    NCBI Gene: 21864
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome 9, Syntenic
  • Mapping Data
    5 experiments
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    17 phenotypes from 1 allele in 1 genetic background
    1 images
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for this spontaneous mutation are small, hyperactive, cannot stand or walk without falling over, display occasional degenerating axons in the optic nerve, and rarely survive beyond 28 days of age.
Sequences &
Gene Models
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Other
Accession IDs
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MGD-MRK-15117
References
more
  • Summaries
    All 7
    Phenotypes 6
  • Earliest
    J:4399 Porter BE, et al., S-laminin: mapping to mouse chromosome 9 and expression in the linked mutants tippy and ducky. Genomics. 1993 Apr;16(1):278-81
  • Latest
    J:236593 Shih EK, et al., The Spontaneous Ataxic Mouse Mutant Tippy is Characterized by a Novel Purkinje Cell Morphogenesis and Degeneration Phenotype. Cerebellum. 2015 Jun;14(3):292-307
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory