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Tg(Mt1-TTR)MRA434Hsas
Transgene Detail
Summary
Symbol: Tg(Mt1-TTR)MRA434Hsas
Name: transgene insertion MRA434, Hiroyuki Sasaki
MGI ID: MGI:4441477
Transgene: Tg(Mt1-TTR)MRA434Hsas  Location: unknown  Genetic Position: Chr11, cytoband A5
Alliance: Tg(Mt1-TTR)MRA434Hsas page
Transgene
origin
Strain of Origin:  (C57BL/6 x C3H)F1 x BALB/c
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Mt1-TTR)MRA434Hsas expresses 1 gene
 
Tg(Mt1-TTR)MRA434Hsas expression driven by 1 gene
 
Mutation detailsHuman TTR was placed under the control of the mouse Mt1 promoter. Ten positive founders were established. The serum TTR concentration was 1.40 mg/dl. (J:159166)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:159166 Sasaki H, et al., Generation of transgenic mice producing a human transthyretin variant: a possible mouse model for familial amyloidotic polyneuropathy. Biochem Biophys Res Commun. 1986 Sep 14;139(2):794-9
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory