Tg(Mt1-TTR)MRA434Hsas
Transgene Detail
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Symbol: |
Tg(Mt1-TTR)MRA434Hsas |
Name: |
transgene insertion MRA434, Hiroyuki Sasaki |
MGI ID: |
MGI:4441477 |
Transgene: |
Tg(Mt1-TTR)MRA434Hsas Location: unknown Genetic Position: Chr11, cytoband A5
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Alliance: |
Tg(Mt1-TTR)MRA434Hsas page
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Transgene Type: |
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Transgenic (Inserted expressed sequence) |
Mutation: |
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Insertion
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Tg(Mt1-TTR)MRA434Hsas expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Homolog in Mouse |
Note |
human |
TTR (7276) |
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Tg(Mt1-TTR)MRA434Hsas expression driven by
1 gene
Transgene expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Mt1 (MGI:97171) |
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Mutation details: Human TTR was placed under the control of the mouse Mt1 promoter. Ten positive founders were established. The serum TTR concentration was 1.40 mg/dl.
(J:159166)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:159166 Sasaki H, et al., Generation of transgenic mice producing a human transthyretin variant: a possible mouse model for familial amyloidotic polyneuropathy. Biochem Biophys Res Commun. 1986 Sep 14;139(2):794-9 |
All: |
3 reference(s) |
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