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Tg(Lhb-TAg)#Plm
Transgene Detail
Summary
Symbol: Tg(Lhb-TAg)#Plm
Name: transgene insertion, Pamela L Mellon
MGI ID: MGI:4442454
Synonyms: LHbeta-Tag, Tg.Rb
Transgene: Tg(Lhb-TAg)#Plm  Location: unknown  Genetic Position: Chr4, cytoband C5-C7
Alliance: Tg(Lhb-TAg)#Plm page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsThe SV40 T antigen gene was placed under the control of the luteinizing hormone beta subunit gene (Lhb). One out of 15 lines produced developed bilateral ocular neoplasms. Marginally detectable mRNA for T antigen was found in the pituitary and considerably higher levels were found in the eye. No T antigen mRNA was detected in any other tissue. (J:10320)
Tumor Data
List all tumor models in MMHCdb carrying Tg(Lhb-TAg)#Plm
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:10320 Windle JJ, et al., Retinoblastoma in transgenic mice. Nature. 1990 Feb 15;343(6259):665-9
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory