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stu Gene Detail
Summary
  • Symbol
    stu
  • Name
    stumbler
  • Feature Type
    heritable phenotypic marker
  • IDs
    MGI:98439
    NCBI Gene: 20906
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome 2, Syntenic
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • PCR
    1
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    21 phenotypes from 1 allele in 2 genetic backgrounds
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mutations in this gene result at first in an abnormal gait. Progressive loss of Purkinje cells results in early death.
Sequences &
Gene Models
less
Molecular
Reagents
less
  • All nucleic 1
    Primer pair 1
Other
Accession IDs
less
MGD-MRK-14638
References
more
  • Summaries
    All 5
    Phenotypes 4
  • Earliest
    J:6464 Caddy KW, et al., Stumbler, a new mutant mouse with cerebellar disease. Brain Res. 1981 Mar 9;208(1):251-5
  • Latest
    J:21507 Frankel WN, et al., The stumbler mutation maps to proximal mouse Chromosome 2. Mamm Genome. 1994 Nov;5(11):659-662
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory