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Pd Gene Detail
Summary
  • Symbol
    Pd
  • Name
    pyrimidine degrading
  • Feature Type
    heritable phenotypic marker
  • IDs
    MGI:97522
    NCBI Gene: 104167
  • Alliance
    gene page
Location &
Maps
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  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome Unknown
Mutations,
Alleles, and
Phenotypes
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Strains C57BL/6J and BDP/J carry the low pyrimidine degrading enzyme activity allele; SJL/J and RF/J carry the high activity allele. Heterozygotes are intermediate. The locus likely affects enzyme structure, as the C57BL/6 enzyme is more thermolabile andhas lower substrate affinity than that of RF.
Sequences &
Gene Models
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Other
Accession IDs
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MGD-MRK-13203
References
more
  • Summaries
    All 3
  • Earliest
    J:235 DAGG CP, et al., A GENE AFFECTING THE RATE OF PYRIMIDINE DEGRADATION IN MICE. Genetics. 1964 Jun;49:979-89
  • Latest
    J:5178 Sanno Y, et al., Studies of a mutation affecting pyrimidine degradation in inbred mice. J Biol Chem. 1970 Nov 10;245(21):5668-76
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory