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nr Gene Detail
Summary
  • Symbol
    nr
  • Name
    nervous
  • Feature Type
    heritable phenotypic marker
  • IDs
    MGI:97375
    NCBI Gene: 18170
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr8:5026602-13700928 bp
    From MGI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, Syntenic
  • Mapping Data
    7 experiments
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    20 phenotypes from 1 allele in 2 genetic backgrounds
    41 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mutations in this gene result in ataxic behavior and progressive retinal degeneration.
Sequences &
Gene Models
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Other
Accession IDs
less
MGD-MRK-12930
References
more
  • Summaries
    All 47
    Phenotypes 41
  • Earliest
    J:14906 Sidman RL, et al., "Nervous," a new mutant mouse with cerebellar disease. Coll Int Centre Natl Recherche Sci. 1970;924:69-79
  • Latest
    J:197421 Li J, et al., Tissue plasminogen activator regulates Purkinje neuron development and survival. Proc Natl Acad Sci U S A. 2013 Jun 25;110(26):E2410-E2419
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory