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H1 Gene Detail
Summary
  • Symbol
    H1
  • Name
    histocompatibility 1
  • Synonyms
    H-1
Location &
Maps
more
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome 7, Syntenic
  • Mapping Data
    12 experiments
Mutations,
Alleles, and
Phenotypes
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This gene was discovered by differences in strain resistance to transplantable tumors. The a and b alleles are found in congenic strains C3H and C3H.K, respectively. At least 6 alleles are known. Antigen is present on many tissues, including transplantable tumors, skin, thymocytes and macrophages.
Sequences &
Gene Models
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Other
Accession IDs
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MGD-MRK-10355, MGD-MRK-10477
References
more
  • Summaries
    All 23
  • Earliest
    J:117 SNELL GD, et al., Histocompatibility genes of the mouse. II. Production and analysis of isogenic resistant lines. J Natl Cancer Inst. 1958 Nov;21(5):843-77
  • Latest
    J:386621 Ohlson LC, et al., Mitoinhibitory effects of the tumor promoter 2-acetylaminofluorene in rat liver: loss of E2F-1 and E2F-3 expression and cdk 2 kinase activity in late G1. J Hepatol. 2004 Jun;40(6):957-62
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
05/19/2026
MGI 6.24 		The Jackson Laboratory