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Dh Gene Detail
Summary
  • Symbol
    Dh
  • Name
    dominant hemimelia
  • Feature Type
    heritable phenotypic marker
  • IDs
    MGI:94889
    NCBI Gene: 109698
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome 1, Syntenic
  • Mapping Data
    14 experiments
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    67 phenotypes from 1 allele in 4 genetic backgrounds
    27 phenotypes from multigenic genotypes
    1 images
    20 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Heterozygotes have multiple skeletal abnormalities and lack a spleen. Immune system function is compromised. Some genetic backgrounds result in reduced fertility, urogenital system abnormalities, and compromised autoimmune response. Homozygotes die within a few days of birth.
Sequences &
Gene Models
less
Other
Accession IDs
less
MGD-MRK-8840
References
more
  • Summaries
    All 27
    Phenotypes 20
  • Earliest
    J:2484 Truslove GM, Genetical studies on the skeleton of the mouse. V. 'Interfrontal' and 'parted frontals'. J Genet. 1952;51(1):115-122
  • Latest
    J:327021 Suto J, Y chromosome of the inbred mouse KK/Ta strain is associated with reduced body size in Y-consomic strains. BMC Res Notes. 2013;6:64
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory