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Acanem1(cre)Jkeb
Endonuclease-mediated Allele Detail
Summary
Symbol: Acanem1(cre)Jkeb
Name: aggrecan; endonuclease-mediated mutation 1, Justus Kebschull
MGI ID: MGI:8448594
Synonyms: Acan-P2A-Cre
Gene: Acan  Location: Chr7:78703231-78764847 bp, + strand  Genetic Position: Chr7, 44.88 cM
Alliance: Acanem1(cre)Jkeb page
Mutation
origin
Strain of Origin:  C57BL/6 x SJL
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase)
Mutation:    Insertion
 
Acanem1(cre)Jkeb expression driven by 1 gene
 
Mutation details: 

CRISPR/Cas9 genome editing technology was used to insert a P2A-Cre cassette immediately upstream of the endogenous stop codon to preserve the gene coding sequence while enabling co-expression of Cre recombinase. (J:393033)

Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Acan (mouse)
Summary of all recombinase alleles driven by Acan.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Acan Mutation:  85 strains or lines available
References
Original:  J:393033 Cheron J, et al., Generation and Validation of an Acan-Cre Mouse Line to Selectively Label Class-B Excitatory Neurons of the Cerebellar Nuclei. Cerebellum. 2026 Aug 12;25(5)
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory